中華民國牙髓病學會

現代牙髓病學:精準與實務的完美結合

When Precision Meets Practice in Modern Endodontics

第18屆第二次會員大會暨第136次學術研討會

2026.08.15–2026.08.16|大臺南會展中心
牙齒意象

大會報到

中華民國牙髓病學會|第十八屆第二次會員大會暨第136次學術研討會

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8月16日(星期日)報到時間:8:30–15:00
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大會議程

09:00–10:20

Art and Practice of Future-Proof Endodontics. Part 1: Diagnosis and Outcomes

SDr. Ove Peters

M謝松志 醫師

10:20–10:50

Coffee Break(熱蘭遮廳)

10:50–12:00

Art and Practice of Future-Proof Endodontics. Part 2: Biologic and Material Science

SDr. Ove Peters

M林郁恆 醫師

12:00–13:30

Lunch(便當於熱蘭遮廳領取)

13:30–15:30

Art and Practice of Future-Proof Endodontics. Part 3: Clinical Practice of Endodontics

SDr. Ove Peters

M何怡青 醫師

15:30–15:50

Coffee Break(熱蘭遮廳)

15:50–17:00

會員大會(General Assembly)

09:00–10:30

育成獎章基礎研究競賽

10:30–10:40

Coffee Break(熱蘭遮廳)

10:40–11:40

育成獎章基礎研究競賽

12:30–13:30

理監專聯席會議

13:30–14:30

牙髓再生術的過去、現在與未來

S林佩玉 醫師

M韓維美 醫師

14:30–15:30

沈默的殺手:牙根吸收的診斷與治療

S陳捷茹 醫師

M邱威智 醫師

15:30–15:50

綜合討論:牙根發育及吸收的診斷與治療決策

S林佩玉、陳捷茹 醫師

M邱威智 醫師

09:00–10:30

育成獎章臨床病例競賽

10:20–10:45

Coffee Break(熱蘭遮廳)

10:45–12:30

育成獎章臨床病例競賽

12:30–13:30

Lunch(便當於熱蘭遮廳領取)

13:30–14:30

Lecture:具代表性的根管案例大解析、現在最熱門的鎳鈦旋轉器械運用

S李偉明 醫師

14:30–15:30

Workshop:現場示範鎳鈦旋轉器械的操作、Q&A交流

S李偉明 醫師

15:30–15:50

Coffee Break(熱蘭遮廳)

09:00–10:20

根管治療牙齒之補綴考量

S姜昱至 醫師

M莊富雄 醫師

10:20–10:50

Coffee Break(熱蘭遮廳)

10:50–12:00

從「形隨器械」到「意隨原形」:鎳鈦金屬相變下的微創修形哲學

S紀智文 醫師

M張淑芳 醫師

12:00–13:30

Lunch(便當於熱蘭遮廳領取)

13:30–14:50

微創根管清潔的藝術:窄小根管的超音波沖洗策略

S陳昱仰 醫師

M蘇文崧 醫師

14:50–15:10

Coffee Break(熱蘭遮廳)

15:10–16:30

根管充填觀念的演進:從側方加壓到矽酸鈣基封填材料的時代

S王正潔 醫師

M黃薰玉 醫師

16:30–17:00

綜合討論:微創牙髓治療的當代策略

S陳昱仰、王正潔 醫師

M黃薰玉 醫師

09:00–10:20

Advances in Vital Pulp Therapy and Root Canal Preparation: Toward Better Biological and Clinical Outcomes Part 1. Basic Background of Endodontics

SDr. Atsushi Tomokiyo

M蔡宜玲 醫師

10:20–10:50

Coffee Break(熱蘭遮廳)

10:50–12:00

Advances in Vital Pulp Therapy and Root Canal Preparation: Toward Better Biological and Clinical Outcomes Part 2. Suggestions for Effective Endodontic Treatment

SDr. Atsushi Tomokiyo

M林芯宇 醫師

12:00–13:30

Lunch(便當於熱蘭遮廳領取)

13:30–14:50

Advances in Vital Pulp Therapy and Root Canal Preparation: Toward Better Biological and Clinical Outcomes Part 3. Vital Pulp Therapy

SDr. Atsushi Tomokiyo

M王馨慧 醫師

14:50–15:10

Coffee Break(熱蘭遮廳)

15:10–16:30

Advances in Vital Pulp Therapy and Root Canal Preparation: Toward Better Biological and Clinical Outcomes Part 4. Root Canal Preparation with NiTi Files

SDr. Atsushi Tomokiyo

M左凱勻 醫師

09:00–10:20

深耕計畫-學習歷程數據如何驅動醫學教育

S李宜恭 醫師

M陳昭安 醫師

10:20–10:50

Coffee Break(熱蘭遮廳)

10:50–11:10

115年機構認定計畫-師資培訓課程

S廖婉萱 醫師

11:10–12:00

深耕計畫-CBME課程

S李苑玲 醫師

12:00–13:30

深耕計畫-Endo CBME 第3次小組討論會議

M李苑玲 醫師

13:30–14:10

牙髓病專科甄試解析

S楊正媺 醫師

14:10–14:50

如何投稿牙髓病科學雜誌

S張耀仁 醫師

14:50–15:10

Coffee Break(熱蘭遮廳)

15:10–15:40

育成獎章優勝者報告(基礎研究論文組)

M戴岑芳 醫師

15:40–16:10

育成獎章優勝者報告(臨床病例組)

M戴岑芳 醫師

演講摘要

S01

Art and Practice of Future-Proof Endodontics

Dr. Ove Peters, PhD

Professor of Endodontics and Head of Clinical Dentistry, University of Queensland, Brisbane, Australia

This talk consists of 5 connected 1 hour-long segments and is collectively designed to translate science into clinical judgment as it related to endodontics. Vital pulp therapy is revisited as a biologically sound, outcome-driven treatment strategy, including its clinical indications, prognostic determinants and economic implications. Instrumentation and obturation are discussed as interdependent pillars of treatment, with emphasis on error avoidance, apical control and the limits of radiographic surrogates for healing.

Endodontic-restorative integration is explored as a decisive factor for long-term success, with clinical outcomes ranked according to restorability, structural integrity and functional demands. The lecture series concludes with an evidence-based appraisal of digital endodontics, distinguishing meaningful diagnostic and workflow advances from technological overreach. Taken together the keynote emphasizes that future-proof endodontics lies not in adopting more technology, but in refining clinical judgment under uncertainty.

Learning Objectives

  • Critically evaluate endodontic outcomes using biological, patient-centred and tooth-survival metrics rather than surrogate process indicators alone.
  • Integrate advances in biology, materials science and technology into rational, evidence-based clinical decision-making.
  • Apply probabilistic and ethical reasoning to treatment planning, prioritizing long-term tooth retention and patient benefit under conditions of uncertainty.
S02

牙髓再生術的過去、現在與未來

The Evolution of Regenerative Endodontic Procedure

林佩玉(Lin PY) DDS

嘉義基督教醫院主治醫師 中華民國牙髓病學會理事暨雜誌編輯 衛福部部定牙髓病科專科醫師

根尖未閉合的未成熟恆牙發生齒髓壞死時,其根管治療會面臨棘手的臨床挑戰,傳統方式是採取根尖成形術後再完成根管充填,但停止發育的脆弱牙根結構將迎來斷裂的高風險甚至縮短牙齒壽命。

牙髓再生術的概念最早可溯及1971年的研究,直到21世紀初期開始應用於臨床治療,不僅能杜絕根管內感染以利根尖周圍組織癒合也能促進牙根繼續發育,增加牙根長度及厚度,改善預後。隨著愈來愈多相關研究及臨床實證支持,牙髓再生術式漸趨成熟,目前已是未成熟恆牙齒髓壞死時的可靠及首要治療選項。

本次演講將回顧牙髓再生術的發展脈絡,分享目前臨床治療步驟準則及操作考量,並介紹未來展望及其他可能應用。

S03

沈默的殺手:牙根吸收的診斷與治療

A Silent Killer:How to Diagnose and Treat Root Resorption

陳捷茹(Chen CJ) DDS

高雄醫學大學附設中和紀念醫院主治醫師 高雄岡山醫院主治醫師 中華民國牙髓病學會副秘書長暨出版委員

牙根吸收是沈默的殺手,經常在不知不覺間造成牙根的嚴重破壞,其臨床上的診斷與治療也面臨重重困難。本次課程將帶領大家了解牙根吸收的分類和機轉,利用錐狀束電腦斷層(CBCT)以獲得更精準的診斷與牙根吸收狀況,並透過臨床案例,剖析造成牙根吸收的可能風險因子,進而探討預防及治療的方式。

S04

根管治療牙齒之補綴考量

Restoration Strategies for Endodontically Treated Teeth

姜昱至(Chiang YC) DDS, PhD

國立台灣大學附設醫院牙體復形美容牙科主任 國立台灣大學牙醫學系教授 曾任國立台灣大學分子醫學影像中心主任 曾任中華民國牙體復形學會理事長

Endodontically treated teeth often present unique restorative challenges due to the loss of tooth structure, altered biomechanics, and increased susceptibility to fracture. Proper restorative planning before and during root canal therapy is therefore essential to ensure long-term function and survival.

Emphasis will be placed on the importance of achieving adequate access and restorative design to improve fracture resistance. The indications, advantages, and limitations of different post systems, such as fiber posts and cast metal posts, will also be discussed. In addition, factors influencing the selection of final restorations, including full crowns, onlays, and adhesive restorations, will be evaluated based on current evidence and clinical guidelines.

Through a review of contemporary studies and clinical examples, this lecture aims to provide a practical framework for treatment planning and restorative decision-making for endodontically treated teeth. Understanding these restorative principles can help clinicians optimize biomechanical stability, enhance prognosis, and improve long-term clinical outcomes.

S05

從「形隨器械」到「意隨原形」:鎳鈦金屬相變下的微創修形哲學

The ABCs and Beyond: Minimally Invasive Endodontics

紀智文(Chi CW) DDS, PhD

國立台灣大學附設醫院主治醫師 國立台灣大學牙醫學系助理教授 曾任臺大醫院新竹分院牙科部副主任

微創牙髓病治療的概念,在保守與效率中取得一個平衡。一個新的治療概念,是眾多理念、技術、與材料的集大成。除了對根管型態發育以及系統知識的掌握,運用牙科手術型顯微鏡的輔助,提升根管治療的視野與能見度,並導入智慧型根管修形系統與高穩定度的根管長度測量儀器,可以讓醫師有效掌握根管的長度以及良好的根管修形效果,搭配安全與有效的根管沖洗概念,進而達到根管內的徹底清潔,最後採用三維緻密根管技術已完成根管內部開口的完美充填,將大幅增加根管治療的成功率。

The concept of Minimally Invasive Endodontics (MIE) seeks a critical balance between tooth structure conservation and clinical efficiency. This modern therapeutic approach represents a synthesis of advanced philosophies, techniques, and materials. Beyond mastering root canal morphology and systematic knowledge, the application of Dental Operating Microscopes (DOM) significantly enhances visibility and precision during treatment. The integration of intelligent root canal shaping systems and high-stability electronic apex locators allows clinicians to accurately control working length and achieve superior canal instrumentation. Combined with safe and effective irrigation protocols, thorough intracanal disinfection can be attained. Finally, the use of three-dimensional (3D) dense obturation techniques to achieve a hermetic seal of the root canal system substantially increases the overall success rate of endodontic treatment.

S06

微創根管清潔的藝術:窄小根管的超音波沖洗策略

The Art of Cleaning in MIE:Strategies for Ultrasonic Irrigation in Narrow Canals

陳昱仰(Chen YY) DDS, MS

白石、怡登、琇品牙醫診所主治醫師 衛福部部定牙髓病科專科醫師

將感染從錯綜複雜的根管解剖結構中徹底去除,始終是根管醫師努力追求的目標,卻也是臨床實踐中最具挑戰性的課題。微創根管治療(Minimally Invasive Endodontics, MIE)在保留齒質結構的同時,也對根管沖洗造成了極大的物理挑戰。

超音波沖洗是目前臨床醫師最常使用的清潔方式之一,但隨著根管錐度與直徑的縮減,沖洗液在狹窄空間中的流動受到限制,導致根尖區的沖洗效果下降。本次演講將從流體動力學的角度進行深度解析,探討超音波沖洗在受限空間中的運作原理,分析其聲流效應(Acoustic streaming)與穴蝕效應(Cavitation)的優勢與侷限,並與其他沖洗技術進行對比。期望能協助與會者在最大程度保留齒質的同時,最佳化根管沖洗效率,在保留齒質結構強度與加強根管沖洗效果的目標之間,尋求最精準的臨床平衡。

S07

根管充填觀念的演進:從側方加壓到矽酸鈣基底封填材料的時代

Evolution of Root Canal Obturation: From Lateral Condensation to Calcium Silicate-Based Sealers

王正潔(Wang CC) DDS

台北醫學大學附設醫院主治醫師 中華民國牙髓病學會雜誌審查委員 衛福部部定牙髓病科專科醫師

根管充填是根管治療成功的重要環節,其主要目的在於封閉根管系統、預防微生物再感染,並促進根尖周圍組織的癒合。過去數十年間,根管充填技術歷經多次演進。傳統的側方加壓充填(lateral condensation)因其操作可預測性與良好的長期臨床成功率,長期被視為標準技術;其後發展的熱垂直加壓充填(warm vertical compaction)則透過加熱牙膠,使材料能更佳地適應複雜的根管系統,提升三維充填的完整性。

近年來,隨著材料科學的進步,矽酸鈣基底封填材料(calcium silicate-based sealers)的出現,逐漸改變根管充填的理念。此類材料具有良好的生物相容性與生物活性,能與牙本質形成礦化界面層(mineralized interfacial layer),並促進羥磷灰石沉積,使以封填劑(sealer)為主導的水合式充填(hydraulic condensation)充填概念逐漸受到重視。

本演講將回顧根管充填技術,自傳統側方加壓與熱垂直加壓充填,到近年矽酸鈣基底封填材料應用的發展歷程,並探討不同技術與材料的臨床優缺點及相關科學證據,進一步討論現代根管治療中根管充填觀念的轉變,以及未來可能的發展方向。

S08

Advances in Vital Pulp Therapy and Root Canal Preparation: Toward Better Biological and Clinical Outcomes

Dr. Atsushi Tomokiyo, PhD

Professor, Graduate School of Dental Medicine, Department of Restorative Dentistry, Hokkaido University, Japan

Dental pulp tissue develops pulpitis when it becomes infected by bacteria. Pulpitis progresses from reversible to irreversible stages, and pulp affected by irreversible pulpitis must be removed. In the past, the entire pulp was removed once irreversible pulpitis was diagnosed. However, it has become clear that pulpitis is located to the site of bacterial invasion, and that uninfected areas of the pulp remain healthy. Furthermore, it has been reported that non-vital teeth have a significantly lower survival rate than vital teeth. Therefore, the importance of vital pulp therapy (VPT), which aims to preserve as much dental pulp as possible, is increasing.

In VPT, a pulp-capping material is placed on the dentin adjacent to the pulp or on the exposed pulp after removing caries and infected tissue. As a result, the pulp is protected by the formation of a reparative dentin or a dentin bridge beneath the pulp capping material. However, no established method exists to reliably distinguish between carious and healthy tooth structure, or between infected and healthy pulp. Although various materials have been used in VPT, the dentin induced by these materials often differs from primary dentin in both structure and function. Based on this background, this presentation will describe current VPT practices, discuss the problems associated with VPT, and highlight key considerations when performing the procedure. In addition, we will introduce our efforts to induce dentin formation that more closely resembles primary dentin after VPT, as well as our attempts to identify caries-related bacteria using photonics.

Pulp extirpation is performed when a large portion of the dental pulp is affected by irreversible pulpitis. During pulp extirpation, the goal is to remove bacteria along with the pulp, and both root canal preparation and irrigation are essential for achieving this. In root canal preparation, it is necessary not only to remove the dental pulp and bacteria (cleaning) but also to create an appropriate angle (taper) that allows for effective root canal irrigation (shaping). Because the ISO standard specifies a 2% taper for stainless steel files, creating a sufficient taper is time-consuming, and it is difficult to confirm whether the taper has been adequately achieved. In contrast, nickel-titanium files have a large taper, enabling sufficient sharpening once they reach the working length. In this lecture, after explaining the characteristics of nickel-titanium files, we will describe a root canal shaping method using the Hyflex EDM OGSF sequence.

S09

學習歷程數據如何驅動醫學教育

李宜恭(Lee YK) MD, MS

大林慈濟醫院急診部主任 大林慈濟醫院教學部主任 慈濟大學兼任副教授

本課程聚焦於「學習歷程數據」如何轉化為提升醫學教育品質的核心動力。隨著數位學習平台、臨床評量工具與電子學習歷程檔案的普及,醫學教育已從傳統經驗導向,逐步邁向以數據支持決策的模式。本課程將系統性介紹學習歷程數據的來源、蒐集與治理方式,並結合學習分析方法,協助教育者理解學生的能力發展軌跡與學習行為。

在應用層面,課程強調如何透過數據視覺化與學習儀表板,提升教學決策的即時性與精準度,並進一步運用於能力本位醫學教育(CBME)、個別化學習設計及臨床教學回饋。學員將學習如何建立早期預警機制、優化評量系統,以及設計以證據為基礎的課程改進策略。

S10

如何投稿牙髓病科學雜誌(JES)及常見投稿錯誤說明

How to Submit to the Journal of Endodontic Science (JES) and Common Submission Errors

張耀仁(Chang YJ) DDS, MS

台大醫院口腔醫學部兼任主治醫師 如意牙醫診所主治醫師 台大醫院口腔醫學部牙髓病受訓醫師 新光吳火獅紀念醫院住院醫師

「牙髓病科學雜誌(Journal of Endodontic Science, JES)」刊載基礎牙髓病學或臨床牙髓病學有關之著作,專注於牙髓病學研究、臨床病例報告、技術分享及病例追蹤,是台灣牙髓病醫師發表學術論文的重要平台。於2026年1月1日起,JES正式通過醫策會「教學醫院評鑑學術性期刊認定標準」,為更符合認定原則,本次將簡介投稿JES流程,以及往年作者投稿時常見的格式錯誤並加以說明。

S11

牙髓病專科醫師考試解析:制度、流程與關鍵規定

Overview of the Endodontic Specialty Board Examination: Structure, Process, and Key Regulations

楊正媺(Yang CM) DDS

高雄榮民總醫院口腔醫學部主治醫師

本演講旨在闡述中華民國牙髓病學會專科醫師甄審制度之架構與評量原則,重點涵蓋報考資格、必要文件與口試病例紀錄審查標準,以及由報名、筆試至口試審查之完整甄審流程。筆試著重基礎知識與臨床應用能力,口試則以病例導向評估臨床思維與決策合理性。另將整理常見退件原因與審查缺失,以釐清制度重點,期能協助受訓醫師正確認知甄審機制,並提升臨床訓練與紀錄品質之符合度。

育成競賽摘要

基礎研究競賽組(大員C)

OR01–OR05|共 5 篇

OR01

Lubrication Effects of Nanodiamonds on Instrument Mechanical Behavior during Shaping of Narrow Root Canals

Kuo C ▲ Hsieh SC*

Department of Oral Medicine, School of Dentistry,
Taipei Medical University Department of Dentistry, Taipei Municipal Wan-Fang Hospital
Endodontic treatment is essential for managing pulpal infection and preserving affected teeth, but
establishing a glide path within narrow, anatomically complex root canals exposes instruments to obstruction,
wear, and fracture. Improving lubricant performance while reducing instrument friction and cumulative
torsional load remains a key challenge. In orthopedics, nanodiamonds (NDs) have been shown to reduce
friction and wear at artificial-joint interfaces while offering biocompatibility and antibacterial activity,
suggesting they may serve as an effective biocompatible lubricant, which motivated this study to explore its
translational application to root canal shaping lubrication. This study evaluated nanodiamonds of different
surface charges as root canal lubricants and their effects on instrument mechanics during glide path preparation
using ProGlider files in narrow canal models. Seven lubricant groups were tested—ddH O, ddH O with
2 2
negatively charged or uncharged 5 nm ND (0.5 mg/mL), 3% NaOCl, 3% NaOCl with negatively charged or
uncharged ND, and RC-Prep—with apically directed force (N) and torque integral (Torque–Time Integral, N·
cm·s) as outcomes (mean values, n = 30). RC-Prep gave the lowest force (5.04 N), while negatively charged
ND in ddH O (6.00 N) and in NaOCl (5.98 N) reduced force relative to ddH O (6.49 N) and NaOCl alone (6.56
2 2
N), and negatively charged ND markedly lowered torque integral (0.138 N·cm·s). Notably, uncharged ND
combined with the ionic NaOCl solution precipitated and aggregated, producing the highest force (7.90 N) and
torque integral (0.488 N·cm·s). Nanodiamond lubrication efficacy thus depends critically on surface charge
and dispersion stability.
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OR02

恆牙蓄意再植術之預後因子:回溯性研究 Prognostic Factors of Intentional Replantation of Permanent Teeth: A Retrospective Study

侯善霖 (Hau J) ▲1 陳冠良(Chen KL)*1 陳昭安(Chen CA)2 郭祉吟(Kuo CY)1 廖怡清(Liao IC)1

1奇美醫療財團法人奇美醫院牙髓病科 2奇美醫療財團法人柳營奇美醫院牙髓病科
當非手術性根管治療(non-surgical root canal treatment)失敗時,蓄意再植術(intentional
replantation)可做為除了根尖手術以外的替代治療方式,特別適用於因解剖位置限制而難以進行根尖手
術之病例,例如第二大臼齒或牙根靠近重要解剖構造等情況。本回溯性研究旨在評估影響恆牙蓄意再
植術治療效果的相關因子。本研究共納入了33名接受蓄意再植術之患者,其中女性22人、男性11人,
共計34顆恆牙,包括4顆前牙、1顆小臼齒、29顆大臼齒,所有案例追蹤時間均超過一年,分析患者基
本資料、術前臨床症狀及其與治療預後的關聯性。研究結果顯示,整體成功率為82.4%;進一步分析
發現,手術前診斷為急性根尖膿瘍(acute apical abscess)之病例其治療成功率低於其他病例,顯示術前
感染狀態會影響蓄意再植術之預後,臨床上應審慎評估並提供作為治療計劃之參考。
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OR03

以CBCT重建二維數位放射影像與機器學習鑑別囊腫與肉芽腫 之先導研究 Differentiating Radicular Cysts from Periapical Granulomas Using CBCT- Reconstructed Two-Dimensional Digital Radiographs and Machine Learning: A Pilot Study

陳炯宏 (Chen JH) ▲1 Arifah Shafyan2 簡名均(Jian MJ)3 林彥昆(Lin YK)3 黃薰玉(Huang HY )*1

1戴德森醫療財團法人嘉義基督教醫院牙髓病科 2Politeknik Elektronika Negeri Surabaya, Surabaya, Indonesia
3國立虎尾科技大學資訊管理系
根尖囊腫(radicular cyst)與根尖肉芽腫(periapical granuloma)為根尖周圍炎常見之慢性病灶,X光
影像中皆呈現放射線透射性(radiolucency),故術前非侵入性鑑別診斷仍具挑戰;病理檢查雖為黃金標
準,但仍需侵入性活檢方能取得。本先導研究為首次提出以錐狀射束電腦斷層(cone-beam computed
tomography, CBCT)重建二維放射影像法(digitally reconstructed radiograph, DRR),並運用四種機器學
習模型:隨機森林(random forest)、XGBoost、LightGBM與支援向量分類器(SVC),以及進一步採用
等權重投票集成法(voting ensemble)整合各分類器之預測結果,來分別探測對根尖囊腫及肉芽腫之鑑
別診斷能力。本研究納入13位根尖手術病人(病理診斷為肉芽腫7例、囊腫6例),病灶平均長、寬、深
為12.59±3.58、11.25±3.49、9.05±3.14 mm,每案例自CBCT擷取通過病灶之8個切面,重建104張
DRR。研究結果顯示,單一分類器中以SVC表現最佳,整體準確率(accuracy)為89.5%、陽性預測精確
度(precision)為 88.2%,並獲得最高之AUC 0.9503,展現優異的單模型判別能力。本研究旨在驗證以
CBCT衍生DRR作為根尖病灶之非侵入性影像表示法,並整合機器學習建立一套可重現之非侵入性術
前診斷框架。研究結果初步證實此框架具備良好的臨床可行性,未來將擴大樣本量驗證泛化能力,期
望提供客觀、可重現且非侵入性之術前輔助診斷工具,協助臨床治療決策。
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OR04

研發仿生磷酸鈣牙根模型評估雙相型玻尿酸膠體 應用於牙髓組織再生 Development of Biomimetic Calcium Phosphate Root Model to Evaluate Biphasic Hyaluronic Acid Gels for Pulp Tissue Regeneration

徐誠毅(Hsu CY) ▲1,2 曾俊傑(Tseng CC)3 李苑玲(Lee YL)*1,2

1國立台灣大學牙醫學院臨床牙醫所 2國立台灣大學附設醫院牙髓病科 3金屬研究中心
雙相型玻尿酸膠體(biphasic hyaluronic acid gels, biHAG)具有良好黏彈性、可注射性、生物
相容性與生物降解性,而進行動物實驗是驗證活體牙髓組織再生成效的必要程序。半異位(semi-
orthotopic)模型,具有可模擬活體實際血液供應情形與實驗成本較低的優點,但是通常使用人類牙根
片段進行實驗,繁複的牙根片段製備、消毒滅菌過程,以及長達數週的牙根脫鈣時間,提高了動物
實驗進行的難度。本研究目的是利用3D列印技術研發標準化仿生磷酸鈣牙根模型(biomimetic calcium
phosphate root model),用以探討不同交聯度biHAG誘導活體牙髓組織再生的成效,並且評估仿生
牙根作為牙髓再生實驗模型的潛力。結果顯示3D列印的仿生牙根表面呈現0.5~3 µm的微孔洞結構與
牙本質小管管徑相似,同時具有良好的生物相容性,並在動物活體實驗中發現仿生牙根只需一到兩
天便可達到足夠的脫鈣結果,大幅降低實驗樣本製備的複雜度與困難度。同時組織學上可以觀察到
仿生牙根周圍無明顯發炎反應,且管腔中可見雙相型玻尿酸膠體降解並有類似牙髓組織的膠原蛋白
纖維組織生成,並伴隨血管長入。研究證實標準化仿生磷酸鈣牙根模型作為牙髓組織再生評估模型
的可行性,可對於牙髓組織工程的支架、細胞與生長因子的不同調控變因進行更進一步的評估,以
建立最佳化的牙髓再生治療術式。
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OR05

牙骨質撕裂牙齒接受根尖周圍手術之預後因素:回溯性研究 Prognostic Factors of Teeth with Cemental Tear Receiving Apical Surgery: A Retrospective Study

李品寬(Lee PK) ▲1 陳冠良(Chen KL)*1 陳昭安(Chen CA)2 郭祉吟(Kuo CY)1 廖怡清(Liao IC)1

1奇美醫療財團法人奇美醫院牙髓病科 2奇美醫療財團法人柳營奇美醫院牙髓病科
牙骨質撕裂(cemental tear)是臨床上相對少見且容易被忽略的病變,症狀與影像表現類似垂直牙根
斷裂、根尖周圍病變或牙周病灶,因此容易造成誤診。對於接受非手術性根管治療後症狀仍持續存在
的牙齒,臨床上常進一步以手術性根管治療介入處理,在手術過程中有時也會發現牙骨質撕裂的情
形,由於牙骨質撕裂會造成牙根與周圍組織的破壞,可能影響術後癒合。本研究目的在針對根尖手術
中發現牙骨質撕裂的牙齒,探討其臨床特徵與根尖手術預後之關聯性。研究回溯收集本院近10年根尖
手術中診斷為牙骨質撕裂的病例,評估相關臨床與影像學的特徵,分析各項因子對治療結果之影響。
結果顯示,牙骨質撕裂相關特徵與根尖手術的預後具有顯著關聯性,若患齒在術前合併有牙周組織破
壞、具有開裂(dehiscence)骨缺損、先前已經做過根尖手術、或牙骨質撕裂範圍延伸至牙根中段者,
其根尖手術治療成功率均顯著降低。臨床治療前將上述四項因子納入評估,將有助於預後判斷的準確
性,可以提供作為治療策略制定與醫病溝通的重要參考。
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臨床病例報告競賽組(大員D)

OC01–OC13|共 13 篇

OC01

Controlled Rotary Shaping and Laser-assisted Disinfection in the Retreatment of a Large Lateral Canal-associated Endodontic Lesion: A Case Report

Hsu YS ▲ Hsieh SC*

School of Dentistry, College of Oral Medicine, Taipei Medical University, Taiwan
Department of Endodontology, Taipei Municipal Wan-Fang Hospital, Taiwan
Lateral canal-associated endodontic lesions are difficult to manage because lateral anatomy is often
inaccessible, unpredictable to disinfect, and commonly obturated only by passive sealer penetration. This case
report presents the non-surgical retreatment of a previously treated maxillary central incisor with a large lateral
canal-associated periradicular lesion, emphasizing controlled rotary shaping and laser-assisted disinfection. A
37-year-old female patient was referred with discomfort in the maxillary anterior region. Tooth 11 presented
with percussion and palpation pain, and active pus discharge was noted after removal of the previous restorative
material. Radiographic examination revealed a large radiolucent lesion on the lateral aspect of the root. CBCT
showed a lesion measuring approximately 6.0 mm x 4.5 mm x 4.9 mm. The diagnosis was previously treated/
acute apical abscess. After dental post and gutta-percha removal under rubber dam isolation, the main canal was
prepared conventionally. The lateral canal was identified under magnification, negotiated with small hand files,
and cautiously enlarged to size #25 using HyFlex™ EDM files. Copious 5.25% sodium hypochlorite irrigation,
passive ultrasonic activation, calcium hydroxide intracanal medication, and adjunctive diode laser irradiation
were used to enhance disinfection. The canals were obturated with gutta-percha and bioceramic sealer using
hydraulic pressure condensation. At the 1-year follow-up, the patient was asymptomatic, and radiographic
examination demonstrated complete healing of the periradicular lesion. This case highlights that successful
healing of a large lateral canal–associated lesion may be achieved through precise anatomical negotiation,
biologically driven disinfection, and adjunctive laser-assisted endodontic treatment.
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OC02

上顎第二大臼齒雙 側牙根使用錐狀射束電腦斷層輔助檢查: 病例報告 Cone-Beam Computed Tomography–Assisted Diagnosis of A Maxillary Second Molar with Two Palatal Roots: A Case Report

葉真吟(Yeh ZY) ▲1 陳冠良(Chen KL)*1 陳昭安(Chen CA)2 郭祉吟(Kuo CY)1 廖怡清(Liao IC)1

1奇美醫療財團法人奇美醫院牙髓病科 2奇美醫療財團法人柳營奇美醫院牙髓病科
上顎第二大臼齒具有複雜且變異性高的根管形態,若無徹底了解牙根構造及根管系統,可能導致
遺漏根管(missing canals)的情形發生,進而造成根管治療的失敗。本報告為一罕見上顎第二大臼齒雙
腭側牙根,使用錐狀射束電腦斷層(cone-beam computed tomography, CBCT)及顯微鏡輔助檢查之臨床
案例,並探討其盛行率、解剖形態分類、診斷方式與臨床治療策略。一名38歲女性,幾個月前因上顎
右側後牙咬合疼痛來就診,根尖X光片顯示上顎右上第二大臼齒具有異常牙根形態,且其中兩牙根分
岔角度較大,進行髓腔開擴後發現有兩個腭側根管開口,利用錐狀射束電腦斷層確認具有兩個獨立的
腭側牙根及四根管系統。根管治療完成後,患者症狀獲得改善,追蹤檢查顯示癒合情況良好。根據文
獻記載,上顎第二大臼齒通常只有一個腭側牙根,出現兩個腭側牙根屬罕見變異,且其依據牙根分離
程度,具有不同類型的解剖形態,有時在二維平面的根尖X光片下牙根影像容易重疊,不易發現牙根
的變異性。此案例利用根尖X光影像及顯微鏡等工具,搭配錐狀射束電腦斷層提供3D影像資訊,有助
於確認根管形態,提高治療品質。
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OC03

人工智慧輔助動態導航系統於鄰近下齒槽神經之根尖手術 AI-Assisted Dynamic Navigation for Apical Surgery Near the Inferior Alveolar Nerve

郭一蒨 (Guo YQ) ▲1 林鴻穎 (Lin HY)2 李苑玲 (Lee YL)*1

1國立台灣大學附設醫院牙髓病科 2國立台灣大學附設醫院口腔顎面外科
動態導航系統可提供即時三維定位資訊,有助於精準移除病灶並降低周邊組織損傷風險。傳統
導航流程需於術前配戴定位裝置拍攝錐狀束電腦斷層(cone-beam computed tomograph, CBCT),再於術
中完成定位註冊(registration)與校正(calibration)。然而臨床上許多患者在治療計畫討論階段即已完成
CBCT 拍攝,若後續決定進行導航手術,往往需重新拍攝CBCT,增加時間成本與輻射暴露。近年來
動態導航系統導入人工智慧(artificial intelligence, AI)影像分割與三維表面重建技術,整合 CBCT 與口
內掃描資料,建立基於解剖結構的虛擬定位註冊流程,簡化術前準備程序。本病例為下顎右側第二小
臼齒於根管再治療過程持續存在根尖膿腫患者,術前 CBCT 顯示根尖病灶與下齒槽神經距離極近,具
有較高神經損傷風險。手術規劃階段匯入病人CBCT(未配戴定位裝置)與口內齒模掃描檔於導航軟體
中進行疊合,並標記下齒槽神經走向,依據三維解剖資訊設計安全的鑽針路徑。術中先使用探針註冊
口內三處牙冠解剖構造特徵點完成校正,而後於動態導航輔助下完成根尖病灶截骨術與根尖切除。術
後患者恢復良好,無出現下齒槽神經損傷症狀。整合AI技術的新型動態導航模式,可大幅縮短並簡化
術前手術設計與規劃時間與流程,並仍能維持其良好的導航精確度,達到高效率且安全的根尖手術治
療。
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OC04

Endodontic Treatment of a Rare Two-Rooted Mandibular Second Molar with Unique Anatomical Morphology: A Case Report

Lee TL ▲ Chou CW Chang SF*

Dental department, Shin Kong Wu Ho-Su Memorial Hospital
The mandibular second molar is the most common site for C-shaped canal systems, with a reported
prevalence of 39.6% in East Asian populations, and typically presents as a single conical root on periapical
radiographs. This report describes the endodontic management of an 18-year-old female patient with an
unremarkable medical history who presented with pulp necrosis and symptomatic apical periodontitis in a
mandibular second molar. Radiographic examination revealed a main mesial conical root and an additional
separate distal root. Following access cavity preparation under a dental operating microscope, a dentine shelf
was identified separating a main C-shaped canal from a distinct distolingual canal, creating a morphology
resembling a semicolon configuration. The primary clinical challenges included a long, narrow isthmus and
a severely curved distolingual canal. Thorough debridement of the isthmus was achieved through meticulous
cleaning and shaping, ultrasonic-activated irrigation, and the placement of a dense calcium hydroxide
intracanal medicament. Meanwhile, highly pre-curved files were used to negotiate the distolingual canal
safely. Favorable periapical healing was observed during follow-up, and the tooth was subsequently restored
with a definitive restoration. In conclusion, multi-angled preoperative radiographs, cone-beam computed
tomography (CBCT), and ultrasonic or sonic irrigation activation are essential for the successful endodontic
management of mandibular second molars with unusual anatomical morphologies.
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OC05

固定式牙橋支台齒之Type IIIA牙中牙顯微根尖手術:病例報告 Endodontic Microsurgery for Type IIIA Dens Invaginatus in an Abutment Tooth of a Long-Span Fixed Prosthesis: A Case Report

楊雅潔 (Yang YJ) ▲1,2 賴博堂 (Lai BT)*2

1部立花蓮醫院牙科 2花蓮慈濟醫院牙科部
本案例為一名 76 歲女性,因左上顎側牙齦持續腫脹至本院求診。臨床檢查發現左前顎側出現圓
丘狀(dome-shaped)突起,環口及根尖放射線影像顯示左上側門齒大範圍根尖透射病灶。錐狀射束電腦
斷層掃描顯示該牙為Oehlers Type IIIA 牙中牙(dens invaginatus),在其偽根管(pseudo-canal)可見過去根
管治療填充物,並由頰側與牙周韌帶相連,推測未治療之主根管為根尖感染的主要來源。患者右上第
一大臼齒至左上第一大臼齒為長牙橋,考量到拆除贋復物進行非手術性根管再治療,將造成患者經濟
負擔,因此選擇顯微根尖手術作為治療方式。手術中進行根尖切除並對主根管進行逆充填。術後一個
月顎側腫脹完全消失,且患者無症狀。18 個月追蹤之影像檢查可見根尖病灶縮小,周圍骨密度增加,
顯示病灶持續癒合中。本案例顯示,Type IIIA牙中牙之感染來源未必侷限於偽根管,主根管牙髓壞死
亦可能為根尖病變形成之關鍵因素。臨床治療計畫除評估根管形態、感染來源、牙髓狀態外,也須考
量贋復物條件及患者需求。對受限於大型固定式贋復物而不適合進行傳統再治療之案例,顯微根尖手
術可作為兼顧感染控制與保存既有贋復物的有效治療選擇。
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OC06

含齒囊腫合併根尖病灶之側門齒牙中牙治療:病例報告 Inflamed Dentigerous Cyst with Periapical Lesion in an Lateral Incisor with Dens Invaginatus: A Case Report

林伊晴(Lin IC) ▲1 莊富雄(Chuang FH)*1,2

1高雄醫學大學附設中和紀念醫院牙髓病科 2高雄醫學大學牙醫學系
齒源性感染與非齒源性感染病灶的臨床處置不同,臨床醫師宜對病灶做全面性的審慎評估。本
文報告一例含齒囊腫(dentigerous cyst)於治療後症狀不消,配合根管治療治癒的病例。患者為18歲男
性,因左上阻生犬齒合併含齒囊腫,6年前在本院口腔顎面外科進行減壓術(decompression)及剜除術
(enucleation)。矯正治療期間,左上前牙區再次腫脹且出現竇管(sinus tract),懷疑為囊腫復發,但至口
腔顎面外科進行活體檢查(biopsy)後排除,故轉診至本院牙髓病科求診。臨床檢查發現,該區有竇管,
無明顯敲痛,左上前牙對敏感性測試(sensibility test)均正常反應。惟放射線與錐狀射束電腦斷層掃描
(cone-beam computed tomography, CBCT)檢查發現左上側門齒牙根近心側有牙中牙(dens invaginatus)的解
剖構造;馬來膠針追蹤亦指向牙中牙位於根尖周圍開口的末端,因此臨床診斷為Oehlers分類第3A型之
牙中牙壞死合併慢性根尖膿腫(chronic apical abscess)。在牙科顯微鏡輔助下,保留主根管牙髓,進行套
疊(invagination)處之治療,並以三氧礦化聚合物(mineral trioxide aggregate, MTA)進行充填。術後三個月
竇管消失不再復發,患齒之敏感性測試仍維持正常反應,並持續追蹤病灶區癒合狀況。齒源性與非齒
源性感染病灶可能出現在同一個區域,臨床醫師應盡量評估各種可能性。而臨床上常以牙髓活性作為
鑑別是否為牙髓引起之感染,於面對牙中牙時,也需有更特異性的考量。
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OC07

手術導板應用於多根牙自體移植術治療:病例報告 Application of Surgical Guides in Autotransplantationof Multi-Rooted Teeth: A Case Report

李芷葳 (Lee JW) ▲ 陳錦松(Chen JS) 劉昀庭(Liu YT) 藍欣(Lan H)*

汐止國泰綜合醫院牙髓病科
自體移植術(autotransplantation)在臨床上可用於取代缺失的牙齒。隨著科技的進步,電腦輔助快
速成形(computer-aided rapid prototyping, CARP)技術、3D列印手術導板、動態導航等開始被應用於自
體移植術,以降低移植牙暴露於口外的時間,減少併發症及提高成功率。本案例為一位35歲男性,因
右下第二大臼齒垂直牙根斷裂而拔除患齒,並立即以左上第三大臼齒自體移植於此拔牙窩。此移植
牙為多牙根的大臼齒,術前透過數位模擬定位,規劃齒槽骨的修磨路徑;術中則搭配 3D 列印手術導
板精準修磨,不僅大幅縮短移植牙在口外的暴露時間,也有效減少了齒槽骨的修磨量。後續完成根管
治療與贋復物製作,術後追蹤無任何症狀,臨床檢查皆正常。本病例報告將探討影響移植成功率的因
素和3D列印手術導板於自體移植術的應用。
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OC08

數位導板導引減壓術上顎第一大臼齒合併根尖周圍骨膜炎 Computer-Aided Planning and Surgical Guiding System in Decompression for Upper First Molar with Periapical Osteoperiostitis

林盈攸(Lin YY) ▲1 藍欣(Lan H)1 吳宗隆(Wu TL)1,2 陳錦松(Chen CS)1,2 劉昀庭(Liu YT)*1

1汐止國泰綜合醫院牙髓病科 2國泰綜合醫院牙髓病科
面對大型根尖病灶(large periapical lesion),當非手術性根管治療成效不彰,需要手術介入時,術
前須先評估病灶的大小及鄰近的解剖構造。若手術的範圍過大,容易引發嚴重的術後併發症;當風
險過高時,可考慮在術前進行減壓術(decompression),縮小病灶範圍再做最終處理。本案例:患者為
40歲女性,右上第一大臼齒曾接受過根管治療,上方有金屬根柱(post)和假牙,數天前出現壓痛的情
形,至本院牙髓病科評估根管重新治療。移除根管內舊有封填材後,腭側根管內持續有大量滲出液,
無法進行根管長度的測量。經過錐狀射術電腦斷層(cone-beam computed tomography)檢查,發現根尖周
圍骨膜炎伴隨上顎竇黏膜增生。若直接進行囊腫摘除會侵犯到上顎竇,於是決定先進行減壓術。但因
遠心頰側牙根根尖和上顎竇間僅有1.4 mm的空間,異常狹小,選擇採用導板輔助定位,順利以鑽針避
開上顎竇穿過狹縫,精準地完成減壓術。術後兩個月上顎竇黏膜恢復正常,腭側根管無明顯滲出液,
完成非手術性根管再治療,術後追蹤十個月,患者症狀改善,上顎竇黏膜恢復正常,放射線學檢查顯
示根尖病灶明顯減小。本案例持續安排追蹤。
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OC09

齒頸部外吸收之手術治療:病例報告 Surgical Management of External Cervical Resorption: A Case Report

顏禎瑩(Yen CY) ▲ 左凱勻(Zuo KY) 張博翔(Chang BS) 邱威智(Chiu WC)*

國立成功大學附設醫院口腔醫學部
牙根吸收是一種因噬牙本質細胞(odontoclast)活性所導致的牙齒硬組織喪失。可依據吸收發生
的位置分為牙根內吸收及牙根外吸收。而其中發生於齒頸部的牙根外吸收,又被稱為齒頸部外吸收
(cervical root resorption)。相較於其他吸收,此疾病較為少見,且目前確切的病因及致病機轉仍未完全
釐清。本文為一名15歲女性患者的右上正中門齒,於幼年時曾因外傷導致脫出並進行復位,間隔7年
後開始感到右上前牙區不適,經臨床及影像學檢查後發現該牙牙髓壞死、根管鈣化、具有根尖病灶,
並伴有齒頸部外吸收的發生。因牙根齒頸部嚴重吸收,根管鈣化嚴重,與患者及家屬商量後決定以手
術方式進行治療。以biodentin進行外吸收窩洞的修補,再以複合樹脂修補齒頸部外吸收的上端部分,
後續進行根尖切除、根尖逆修行,並以三氧礦化聚合物(mineral trioxide aggregate, MTA)完成根尖逆充
填。術後7個月追蹤癒後良好,病人無主訴症狀,維持持續追蹤中。藉由手術介入同時處理齒頸部外
吸收及牙髓壞死、根管鈣化的問題,在後續追蹤中病人反應良好,可以作為相關案例治療的參考。
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OC10

脫落齒併發牙根外吸收之未成熟雙側上顎正中門齒的 再生牙髓治療 Regenerative Endodontic Procedures for Immature Bilateral Maxillary Central Incisors with Avulsion and External Root Resorption

張斯媛(Chang SY) ▲1 何怡青(Ho YC)1,2 楊淑芬(Yang SF)1 蔡佳倫 (Tsai CL)*1,2

1台北榮民總醫院口腔醫學部 2國立陽明大學牙醫學院
發炎性牙根外吸收(external inflammatory root resorption)為未成熟恆牙脫落再植後可能發生的嚴
重併發症。雖然傳統上以長期氫氧化鈣治療合併根尖成形術處理,但近年再生牙髓治療亦被提出作為
治療選擇。本病例報告一位8歲女孩,因跌倒導致牙根仍未發育完全之雙側上顎正中門齒脫落合併非
複雜性牙冠斷裂,口外乾燥時間為半小時,後續進行復位與固定。三個月時檢查發現雙側上顎正中門
齒對敏感性測試(sensibility test)均無反應,根尖片顯示放射線透射性根尖病灶合併多處側方牙根外吸
收。雙側上顎正中門齒診斷為牙髓壞死合併無症狀性根尖周圍炎及發炎性牙根外吸收。與病患及家屬
溝通後決定進行再生牙髓治療。於髓腔開擴後,以2.5%次氯酸鈉及17% EDTA進行化學清創輔以被動
超音波沖洗(passive ultrasonic irrigation),並置放氫氧化鈣,密切追蹤後,放射線影像顯示吸收病灶已
獲控制。以根管銼針刺激根尖組織誘導出血,並於血塊上方覆蓋膠原蛋白(Collacote®)及牙本質生物活
性修補材(Biodentine®),後續以樹脂完成冠部復形。經一年追蹤,病患無任何臨床不適,放射學影像
顯示根尖病灶完全癒合且根尖口閉合。本病例結果顯示,對於脫落後再植且併發發炎性外吸收之未成
熟恆牙,在適當感染控制後施行再生牙髓治療,能成功終止吸收進程並促進牙根進一步發育,為保留
患牙的可行治療策略。
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OC11

以再生牙髓治療處理內吸收合併穿孔之上顎側門齒:病例報告 Regenerative Endodontic Therapy of a Maxillary Lateral Incisor with Perforated Internal Root Resorption: A Case Report

陳柏宏(Chen PH) ▲ 吳宗隆(Wu CL)*

國泰醫療財團法人國泰綜合醫院口腔醫學部牙髓病科
牙根內吸收的病因尚無定論,目前治療原則大多以移除根管內的組織並徹底清創封填根管為主,
然而針對內吸收範圍較大,甚至伴隨牙根穿孔的案例,其預後會因為破孔的大小、位置以及剩餘齒質
結構而有所影響。再生牙髓治療(regenerative endodontic therapy)則多用於牙髓壞死且未發育完全之年
輕恆牙,期望能增加牙根的長度及根管壁的厚度,達到加強牙齒結構的效果。本次案例報告描述一位
14歲的患者,於例行性放射線檢查中發現其左上側門齒有鄰接面齲齒,並於根尖三分之一處有一卵圓
形的放射線透射區,以錐狀射束電腦斷層掃描(cone-beam computed tomography)確認有牙根內吸收伴
隨穿孔及側方病灶,因考量到病患年紀較輕、剩餘齒質較薄,且根尖伴隨有多處側方穿孔,後續決定
以再生牙髓治療處理,期望能增加內吸收區域管壁的厚度。在髓腔開闊後,於顯微鏡下可觀察到內吸
收區域有暗紅色的軟組織,刮除發炎組織後以氫氧化鈣作為根管內用藥,四週後回診可見原先暗紅色
的軟組織已大半消退,且於顯微鏡下可見疑似近心穿孔的區域,後續誘導出血至內吸收區域的冠部,
並以ProRoot® MTA進行封填,冠部以樹脂復形。一年半追蹤可見側方病灶逐漸癒合,且原先內吸收區
域的根管壁有明顯增厚的趨勢,顯現治療之成效。
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OC12

顯微根尖周圍手術後遲發發炎性牙根外吸收之17年追蹤病例報告 Late-Onset Severe External Inflammatory Root Resorption Following Successful Endodontic Microsurgery: A 17-Year Follow-Up Case Report

陳勁宇(Chen CY) ▲1 蔡佳倫 (Tsai CL)1,2 楊淑芬(Yang SF)1,2 何怡青 (Ho YC) *1,2

1台北榮民總醫院口腔醫學部 2國立陽明交通大學牙醫學院
顯微根尖手術(endodontic microsurgery)為治療持續性根尖病變之重要術式,整體成功率高,惟極
少數病例於長期追蹤後仍可能因感染持續或其他因素而導致病灶復發。本病例為61歲女性,上顎右側
犬齒及第一小臼齒曾於2008年在本院接受顯微根尖手術並以三氧礦化聚合物(mineral trioxide aggregate,
MTA)進行逆充填,術後顯示癒合良好。然而術後17年,患者因反覆牙齦腫脹及瘻管形成就診,臨床
檢查可見上顎右側犬齒頰側瘻管,根尖片及錐狀射束電腦斷層掃描(cone-beam computed tomography,
CBCT)顯示根尖區具有放射線透射性病灶,並伴隨嚴重不規則硬組織缺損,診斷為已根管治療牙齒
(previously treated)暨慢性根尖膿腫(chronic apical abscess),且具嚴重外部發炎性牙根吸收(external
inflammatory root resorption),遂進行再次顯微根尖手術。術中發現頰側骨開窗(fenestration),移除發
炎組織及既有根尖逆充填材料後,發現根尖區大範圍不規則之牙根缺損。根尖窩洞修形後,以生物
陶瓷材料 CeraPutty(Meta Biomed, Cheongju, Korea)進行逆充填,病理檢查結果為根尖肉芽腫(periapical
granuloma)。本病例為顯微根尖手術後長達17年,卻出現病灶復發並伴隨嚴重外部發炎性牙根吸收之
罕見病例。CBCT於術前評估吸收缺損範圍具重要診斷價值,再次顯微根尖手術搭配生物陶瓷材料可
有效處理複雜缺損並保留自然牙,同時提醒臨床醫師重視術後長期定期追蹤之必要性。
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OC13

下顎牙根未完全發育小臼齒之根管再治療:病例報告 Retreatment of Immature Root Development Mandibular Premolar: A Case Report

楊采蓁(Yang TC) ▲ 凌毓辰(Ling YC)*

天主教耕莘醫療財團法人耕莘醫院牙髓病科
牙根未完全發育恆牙如在根管治療後仍有症狀,可依照根管的可治療性、可及性等情況來選擇
不同的再治療方式,包含拔牙、手術性根管再治療或非手術性根管再治療,非手術性治療可合併再生
牙髓治療(regenerative endodontic therapy)或根尖成形術(apexification)。本病例為18歲女性,左下第一
小臼齒曾於2016至2018年間於他院進行未完全發育牙根之根管治療術式,於2024年因左下牙齦腫脹由
診所轉診至本院牙科進行評估與治療。臨床檢查發現左下第一小臼齒頰側區域有牙齦腫脹,牙冠有變
色情形,敲診及觸診皆無疼痛。放射線檢查顯示左下第一小臼齒冠部有不同放射線不透性之填補材
料,根管內部也有不規則分布之放射線不透性影像,根尖呈現未完全發育之開放型根尖,根尖周圍有
放射線透性病灶,病灶內部伴隨放射線不透性影像於牙根近心處。治療計畫先進行非手術性根管再治
療合併根尖成形術並追蹤。術後一年追蹤顯示病灶已接近完全癒合,術前放射線檢查顯示之病灶內部
放射線不透性影像仍存在於根尖處,但位置隨病灶之癒合已有改變,後續持續進行追蹤。此病例報告
顯示未完全發育牙根以非手術性根管再治療合併根尖成形術可達到良好之治療效果。
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貼示摘要

P01–P29|共 29 篇

P01

Presence of Second Mesiobuccal Canal of Permanent Maxillary First Molars is Related to the Existence of Multiple Roots in Permanent Maxillary First Premolars: A CBCT Study in a Taiwanese Population

Dai ZJ ▲ Chen YJ Shieh YS Wu YC*

Department of Operative Dentistry and Endodontics, College of Oral Medicine, Tri-Service General Hospital and
National Defense Medical University, Taipei, Taiwan
Understanding root and canal morphology is critical for successful endodontic treatment. Detecting
predictors of a second mesiobuccal (MB2) canal in permanent maxillary first molars (PMFMs) may improve
diagnostic accuracy. This study examined the relationship between root number of permanent maxillary
first premolars (PMFPs) and MB2 occurrence in PMFMs in a Taiwanese population. CBCT scans from 645
patients were reviewed, and 188 met the inclusion criteria, yielding 752 teeth (376 PMFPs, 376 PMFMs).
Root number and canal morphology were classified using Vertucci’s system. MB2 prevalence and bilateral
symmetry were assessed. Associations between PMFP root number and MB2 occurrence were analyzed with
chi-square tests and multivariable logistic regression adjusted for sex, age, and side. Among PMFPs, 60.9%
had one root, 37.5% had two roots, and 1.6% had three roots. In single-rooted PMFPs, the most common
configurations were Types I, III, IV, and II. In PMFMs, the mesiobuccal root most frequently showed Type
I (42.0%), followed by Type IV (30.8%) and Type II (23.6%). Males had a higher prevalence of multi-
rooted PMFPs and MB2 canals than females. Logistic regression revealed that multiple-rooted PMFPs were
independently associated with MB2 occurrence in PMFMs, with an adjusted odds ratio of 2.081 (p < 0.001).
Bilateral symmetry was high in both PMFP root number (81.4%) and MB2 presence (85.1%). Multiple-
rooted PMFPs were strongly correlated with MB2 occurrence in PMFMs. PMFP morphology may serve as a
predictive indicator for MB2 detection.
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P02

Complex Root Canals of Maxillary Second Premolars Are Associated with the Occurrence of Multiple Roots in Maxillary First Ppremolars: A Cross-Sectional Cone-beam Computed Tomography Study in a Taiwanese Population

Chen YJ ▲1 Dai ZJ1 Shieh YS1,2 Wu YC*1

1Department of Operative Dentistry and Endodontics, College of Oral Medicine,
Tri-Service General Hospital and National Defense Medical University
2Department and Graduate Institute of Biochemistry, National Defense Medical University
This retrospective cone-beam computed tomography (CBCT) study investigated the association between
the root number of permanent maxillary first premolars (PMFPs) and the canal complexity of adjacent
permanent maxillary second premolars (PMSPs) in a Taiwanese population. CBCT images of 600 fully
developed, untreated teeth (300 PMFPs and 300 PMSPs) from 150 patients (69 females, 81 males; aged
20–83 years) were analyzed. PMSP canal morphology was categorized using Vertucci’s classification, and
multivariable logistic regression was adjusted for sex, age, and side. Results showed that 56% of PMFPs were
single-rooted and 44% were multi-rooted. For PMSPs, 46.7% exhibited complex canal systems, predominantly
featuring Vertucci Type I (53.3%), Type III (16.7%), and Type II (12.3%). Males had a significantly higher
prevalence of multi-rooted PMFPs and complex PMSP canals (p < 0.05). Multivariable regression revealed
that multi-rooted PMFPs were significantly associated with complex PMSP canals, presenting an adjusted
odds ratio of 2.507 (p < 0.001). Furthermore, high bilateral consistency was observed for both PMFP root
number (77.3%) and PMSP canal category (81.3%). In conclusion, a significant anatomical correlation exists
between PMFP root number and PMSP canal complexity. Multi-rooted PMFPs serve as a strong predictor for
complex PMSP canal systems, and high bilateral symmetry supports contralateral reference during endodontic
planning. Clinically, a standard periapical radiograph capturing both premolars offers a practical, low-radiation
alternative to CBCT for preliminary assessment, optimizing treatment efficacy while minimizing patient
radiation exposure.
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P03

Prevalence of MB2 Canal in Maxillary Molars of Han Population

Wu JY ▲ Chiang HS Shieh YS Wu YC*

School of Dentistry & Department of Dentistry, National Defense Medical University and Tri-Service General Hospital
The second mesiobuccal canal (MB2) is one of the most common anatomical variations in maxillary
molars. Failure to identify and treat this canal during root canal treatment may result in persistent infection,
apical periodontitis, and unfavorable treatment outcomes. However, evidence regarding the prevalence of
MB2 in the Han population remains fragmented. The aim of this study was to evaluate the prevalence of MB2
in maxillary first and second molars of the Han population and to investigate the influence of sex and tooth
side through a systematic review and meta-analysis. Following the PRISMA guidelines, studies published
before August 17, 2025 were identified from PubMed, MEDLINE, Scopus, and ClinicalKey databases. Only
studies using cone-beam computed tomography (CBCT) to assess MB2 prevalence in permanent maxillary
molars of Han populations were included. A random-effects model was applied for meta-analysis. Fourteen
studies involving 15,639 subjects and 35,929 teeth were included. The pooled prevalence of MB2 was 63.7%
in maxillary first molars and 23.3% in maxillary second molars. Male subjects exhibited significantly higher
odds of having MB2 than females, with odds ratios of 1.532 and 1.790 for maxillary first and second molars,
respectively. No significant difference was observed between the left and right sides. Within the limitations
of this study, MB2 was highly prevalent in maxillary molars of the Han population, particularly in maxillary
first molars. Clinicians should carefully evaluate the presence of MB2 and consider the use of CBCT and
microscopic endodontic techniques to improve canal detection and treatment outcomes.
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P04

Development and Evaluation of Automatic Access Opening Planning for Root Canal Treatment

Ho YC ▲1,2 Chen BH1,2 Chang SL3 Wu KC3 Chen CW*3

1Department of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan
2College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan
3Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
To reduce human burden and fatigue in repetitive operations, robot-assisted endodontics with automatic
pre-operative planning has recently emerged. This ex vivo study developed an automatic access opening
planning algorithm and evaluated its accuracy for root canal treatment. Thirty-one extracted single- and two-
canal human teeth (premolars and canines) were scanned using micro-computed tomography (CT). The
CT images were input into a particle-swarm-optimization-based algorithm to determine the optimal access
opening path. To minimize planning complexity for these specific tooth types, the cross-sectional shape of
the access opening was modeled as an ellipse. Three general dentists then reviewed the planning result, either
approving or modifying to meet clinical standards. The variation between the dentists (DD) and the variation
between the algorithm and dentists (AD) were compared using paired t-test and Wilcoxon signed-rank test to
verify the accuracy of the algorithm. By comparing DD and AD in linear, angular, 2D and 3D metrics, there
was no statistical difference between them or the difference was clinically negligible. The 3D spatial and 2D
cross-sectional overlap between the algorithm-planned and dentist-approved paths exceeded 80%. In this ex
vivo study, the algorithm demonstrated clinically acceptable accuracy as general dentists did. In the future, the
shape of the access opening can be set as an irregular shape to better match pulp chamber anatomy, increasing
the planning accuracy and therefore preserving more tooth structure.
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P05

Impact of Submicron Diamond on Enterococcus faecalis Biofilm Formation and Viability

Septiani C ▲1 Huang HM1 Hsieh SC*1,2

1Department of Oral Medicine, School of Dentistry, Taipei Medical University, Taipei, Taiwan
2Department of Endodontology, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Persistent Enterococcus faecalis biofilm in root canals remains a major challenge in endodontic treatment.
Sodium hypochlorite (NaOCl) is the standard irrigant used in endodontic procedures, yet its efficacy remains
limited by delivery method and biofilm resistance. Our previous studies have demonstrated that 500 nm
submicron diamonds (SMD) supplemented in NaOCl with sonic and ultrasonic activation effectively remove
smear layer and hard-tissue debris, and show superior E. faecalis biofilm removal under SEM, CLSM, and
Micro-CT. This preliminary study evaluates SMD-supplemented NaOCl efficacy against E. faecalis biofilm
using quantitative formation and viability assays. Thirty extracted single-rooted premolars are being enrolled.
The canals were prepared with ProTaper® Gold F2 (Dentsply Sirona, USA), inoculated with E. faecalis (OD
= 0.1), and incubated for 21 days to establish biofilm. The teeth were divided into six groups (n=5) and
received different irrigation protocols: positive control, standard 3% NaOCl via manual irrigation, sonic
activation, and ultrasonic activation, and SMD-supplemented 3% NaOCl (500 nm, 10 mg/mL) via sonic and
ultrasonic activation. Biofilm was quantified with crystal violet staining for biofilm formation and resazurin-
based detection for biofilm viability. Preliminary results showed consistent reduction across all irrigated
groups. Both SMD+Sonic (formation: 0.081 ± 0.015; viability: 0.238 ± 0.092) and SMD+Ultrasonic
(formation: 0.040 ± 0.0001; viability: 0.042 ± 0.0008) groups showed significantly greater biofilm reduction
compared to all standard NaOCl groups (p < 0.05), with no significant difference between them. Our findings
demonstrated that SMD-supplemented NaOCl enhanced E. faecalis biofilm removal and decreased biofilm
viability regardless of activation method.
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P06

Classification of Autotransplantation of Teeth and Clinical Outcome

Wen JH ▲ Tsai LY Wang HH Huang YW*

Taipei Medical University Wan Fang Hospital
Autotransplantation of teeth (ATT) is a reliable treatment option for replacing missing teeth. However,
the influence of recipient socket conditions on treatment outcomes remains unclear. This retrospective study
evaluated the effect of recipient socket conditions on the clinical outcomes of ATT. Fifty-five ATT cases were
reviewed, with a mean follow-up period of 31 months. Recipient sites were classified into four categories
according to the size relationship between the recipient socket and donor tooth: Class 1 (recipient socket larger
than the donor tooth), Class 2 (recipient socket similar in size to the donor tooth), Class 3 (recipient socket
smaller than the donor tooth), and Class 4 (edentulous ridge recipient site), with Class 0 representing donor
teeth affected by periodontitis. Clinical outcomes and cumulative survival rates were analyzed. The effects of
patient age, use of a 3D replica, open apex, splinting time, and extraction reason on treatment outcomes were
also evaluated. Survival rates were 100% for Class 1, 3, and 4 sockets, 94.4% for Class 2 sockets, and 75%
for Class 0 donor teeth. The use of a 3D analog significantly improved outcomes (p = 0.037), while procedural
discrepancies negatively affected results (p < 0.01). ATT demonstrated favorable clinical outcomes across
different recipient socket conditions. The proposed recipient socket classification may assist clinicians in
selecting appropriate surgical approaches and improving treatment predictability.
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P07

Association between Bone-Modifying Agent Therapy and Periapical Healing Following Root Canal Treatment

Liu HC ▲1 Wang CH1 Wang YT2 Huang YW1 Wang HH*1

1Department of Dentistry, Wan-Fang Hospital, Taipei Medical University
2Department of Pharmacy, Wan-Fang Hospital, Taipei Medical University
Bone-modifying agents (BMAs) are widely used for the management of osteoporosis and cancer-related
bone diseases and may influence bone metabolism and healing. The aim of this study was to evaluate the
association between BMAs exposure and the healing of apical periodontitis following non-surgical root canal
treatment (NSRCT). Patients who received oral or injectable BMAs and underwent NSRCT at Wan Fang
Hospital between January 2022 and September 2025 were reviewed. Eligible cases had periapical radiographs
available for healing assessment using the periapical index (PAI). A total of 92 cases were included. Patients
with BMAs exposure exceeding one year demonstrated a significantly higher rate of PAI improvement than
those with less than one year of exposure (68.4% vs. 43.8%; OR = 2.79, 95% CI: 1.05–7.40; p = 0.040).
Within the limitations of this study, BMAs exposure for more than one year was associated with improved
radiographic healing following NSRCT. However, a causal relationship could not be established. Further
prospective studies with appropriate control groups and larger sample sizes are needed to confirm these
findings and clarify the independent effect of BMAs exposure on periapical healing.
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P08

牙髓幹細胞來源外泌體與MTA對牙髓幹細胞之影響 Effects of Dental Pulp Stem Cell-Derived Exosomes and MTA on Human Dental Pulp Stem Cells

黃翠賢(Huang TH) ▲*1,2 王力朋(Wanitkitkurpol P)1 林奕廷(Lin YT)2 張家源(Chang JY)2 黃尚志(Huang ST)2 陳琬蓁 (Chen WC)1,2 洪啓智 (Hong CJ)1,2

1中山醫學大學口腔醫學院 2中山醫學大學附設醫院牙髓病科
三氧化礦物聚合體(mineral trioxide aggregate, MTA)因具良好生物相容性及促進硬組織修復能力,
廣泛應用於活髓治療及根管治療。近年來,牙髓幹細胞(dental pulp stem cells, DPSCs)來源之外泌體
(extracellular vesicles, EVs)因具有促進細胞增生及組織再生之潛力,逐漸成為牙髓再生研究的重要
方向。本研究評估DPSC來源EVs與MTA萃取液單獨或聯合應用對人類DPSCs細胞活性之影響。人類
DPSCs(第3–10代)培養於DMEM/MSCM混合培養液中。EVs經無血清培養、0.22 μm過濾及300 kDa切
向流過濾純化,並以ZetaView®分析粒徑與濃度。MTA依ISO 10993-12製備萃取液後稀釋為不同濃度。
DPSCs分別接受EVs、MTA萃取液或兩者聯合處理,於24、48及72小時以MTT assay評估細胞活性。結
果顯示,DPSC來源EVs於各濃度及各時間點均可維持或提升細胞活性,顯示其具有良好生物相容性及
促進增生能力。MTA萃取液呈濃度依賴性效應,低濃度可維持或促進細胞活性,高濃度則隨培養時間
延長產生抑制作用。與單獨使用MTA萃取液相比,EVs與MTA聯合處理於24、48及72小時皆可提高細
胞活性,顯示EVs可部分緩解高濃度MTA造成之抑制效應。綜合而言,DPSC來源EVs具有良好生物相
容性及促進DPSCs增生之能力,與MTA聯合應用可改善MTA對細胞活性之抑制作用,顯示其於牙髓再
生治療具有潛在應用價值,未來仍需進一步探討其促進牙髓修復及礦化分化之機轉。
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P09

下顎第二小臼齒 C 型根管之處置:病例報告 Management of a C-Shaped Root Canal in a Mandibular Second Premolar: A Case Report

江依芸(Chiang IY) ▲ 蘇映輝(Su YH) 莊富雄(Chuang FH)*

高雄醫學大學附設醫院牙科部牙髓病暨牙體復形科
根據一項透過橫截面分析法,探討華人族群下顎第一小臼齒的根管形態的研究。約五成左右的
牙齒具備單一根管,其餘則包含雙根管(22%)、C形根管(18%)、環狀根管(6%);且這類變異多出現在
根尖3至6毫米的區域。下顎第二小臼齒根管形態相對單純,約9成是單一根管、單一根尖孔;C形根
管更是少之又少。然而靠近根尖處的根管變異,與治療預後息息相關。如何在達成良好的修形與清潔
前提之下,盡可能保留最多齒質,對保留自然牙有極大幫助。此20歲男性因右下第二小臼齒齲齒造成
的牙髓壞死而接受根管治療,患者初診時已無明顯臨床症狀。經髓腔開闊與清創以及根尖放射影像,
確定為C形根管小臼齒。在顯微鏡下確認峽部位置與頰側及舌側根管開口後,以超音波探頭搭配次氯
酸鈉沖洗完成冠部向根尖擴大技術(crown-down preparation)。隨後以鎳鈦旋轉銼針搭配次氯酸鈉沖洗
完成頰側、舌側根管及峽部的清創與修型。隨後以垂直熱加壓充填法搭配AH Plus 根管封填劑封填根
管。一週回診追蹤患者沒有臨床症狀,建議患者製作臨時牙冠持續追蹤觀察。相對於下顎第二大臼
齒,下顎小臼齒C形根管在臨床比較少見,操作空間較小,發生平台(ledge)或穿孔的機率也較高。此
案例以顯微鏡搭配超音波探頭,盡可能保留更多齒質,也完成根管的清潔與修形。
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P10

Endodontic Management of S-Shaped Root Canals: A Case Series

Hsiao HY ▲1 Hung WC1,2 Lin HY1 Wang CC1 Yang CY1 Wang SH1 Chang CW*1,3

1Devision of Endodontic, Dental Department, Taipei Medical University Hospital
2School of Oral Hygiene, College of Oral Medicine, Taipei Medical University
3School of Dentistry, College of Oral Medicine, Taipei Medical University
Curved root canals increase the risk of procedural complications during endodontic treatment, including
canal transportation, perforation, and instrument separation. S-Shaped root canals, characterized by double
curvatures, present a particularly challenging anatomical configuration because maintaining the original canal
pathway during instrumentation can be difficult. Appropriate treatment planning and instrument selection are
therefore essential for successful management. This report presents three cases of S-Shaped root canals, including
two maxillary second premolars and one mandibular second premolar. Preoperative radiographic examination
revealed double curvatures in all teeth. Canal negotiation and glide path establishment were performed using
pre-curved stainless steel hand files, followed by canal shaping with nickel–titanium instruments. Root
canal obturation was completed using the hydraulic filling technique. Management of S-Shaped root canals
requires careful assessment of both coronal and apical curvatures during treatment planning. Establishment
of a reproducible glide path before rotary instrumentation is critical, as abrupt changes in canal direction
increase the risk of canal transportation, ledge formation, perforation, and instrument separation. Instrument
selection, flexibility, and shaping sequence should be considered to minimize unnecessary dentin removal while
maintaining the original canal anatomy. Recognition of these anatomical challenges is essential for reducing
iatrogenic complications and improving treatment predictability.
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P11

下顎第一大臼齒遠心單牙根具三根管之非手術性根管治療: 案例報告 Nonsurgical Endodontic Treatment of Mandibular First Molars with Three Root Canals in Single Distal Root: A Case Report

陳遠揚(Chen YY) ▲1 張仁豪(Chang JH)1 賴聖曜(Lai SY)1 王偉全(Wang WQ)1 涂 明君(Tu MG)*1,2

1中國醫藥大學附設醫院牙醫部 2中國醫藥大學牙醫學系
成功根管治療的關鍵在於徹底清創與緻密充填整個根管系統。下顎第一大臼齒常具三根管或四
根管。遠心牙根出現三個根管的解剖變異極為罕見,若在術前或術中忽略,常導致治療失敗。本報告
呈現一例下顎第一大臼齒遠心三根管病例,並探討其臨床診斷與治療策略。病例:一位男性患者因右
側下顎第一大臼齒自發性疼痛到本院進行評估治療,臨床與放射線檢查診斷為牙髓為不可逆性牙髓炎
(irreversible pulpitis),根尖診斷為症狀型根尖周圍炎(symptomatic apical periodontitis)。於本院進行髓腔
開擴後,確認到近心頰側、近心舌側、遠心頰側、遠心舌側共計四根管。在治療過程均採用鎳鈦旋轉
器械搭配手動器械進行擴大清創並且搭配超音波沖洗。進行幾次的治療後患者表示仍然有症狀,因此
懷疑有遺漏的根管。使用超音波器械在近心及遠心狹部(isthmus)移除周圍齒質進行探測後,最終懷疑
有遠心中央根管(middle-distal canal),因此拍攝錐狀束電腦斷層掃描(cone beam computed tomography,
CBCT)進行確認。完成遠心中央根管之清創後,患者症狀改善。最終使用垂直加熱填壓法完成根管
充填。結論 : 針對此類罕見複雜根管系統,臨床上須仰賴牙科手術顯微鏡 (dental operating microscope,
DOM) 探測根管開口。同時可使用超音波器械或者長柄慢速車針(long neck low speed bur) 沿著狹部進
行挖溝(troughing)移除部分牙本質以便暴露出額外的根管開口。錐狀束電腦斷層掃描被認為是進行治
療前確認根管位置的黃金標準。
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P12

上顎第一大臼齒嚴重彎曲根管之重新治療:病例報告 Endodontic Retreatment of Severely Curved Root Canals in a Maxillary First Molar: A Case Report

藍欣(Lan H) ▲*1 陳錦松(Chen CS)1,2 江宜蓁(Chiang YC)1 劉昀庭(Liu YT)1

1汐止國泰綜合醫院牙髓病科 2國泰綜合醫院牙髓病科
上顎第一大臼齒常具有複雜且變異性高的根管解剖形態,其中近心頰側根管常見明顯的彎曲,且
伴隨第二近心頰側根管的存在,使得初始根管治療難度大幅提升。當出現遺漏根管、根管清創不足或
因根管嚴重彎曲導致平台(ledge)、偏移(transportation)出現時,可能造成持續性的髓腔內感染,進而需
要根管重新治療。彎曲根管的重新治療極具挑戰性,本案例藉由牙科顯微鏡、超音波器械及旋轉鎳鈦
器械的輔助,安全移除舊有充填物,在盡量不偏移原有彎曲根管的路徑下,徹底清創並緻密封填。患
者後續完成贋復物製作,術後追蹤無不適,臨床檢查皆正常。
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P13

Endodontic Management of Mandibular Second Molar Fused with a Paramolar Tubercle: A Case Report

Lai JY ▲1 Hung WC*1,2 Chang CW1,3 Lin HY1 Wang CC1 Yang CY1 Wang SH1

1Division of Endodontic, Dental Department, Taipei medical University Hospital
2School of Oral Hygiene, College of Oral Medicine, Taipei Medical University
3School of Dentistry, College of Oral Medicine, Taipei Medical University
Successful non-surgical root canal treatment relies on effective elimination of infection from the root
canal system. However, anatomical variations of teeth can present significant challenges during treatment.
These variations may occur in the crown, root, or both, such as tooth fusion or accessory cusps, leading to
complex root canal morphology. Therefore, careful evaluation of dental anatomy before treatment is essential.
This case report presents the endodontic management of a rare mandibular second molar fused with a
paramolar tubercle.
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P14

類似穿孔解剖變異之上顎第一大臼齒非手術性根管治療: 病例報告 Anatomical Variations Mimicking Perforation in Nonsurgical Root Canal Treatment of Maxillary First Molars: Two Cases Report

林郁恆(Lin YH) ▲* 陳姿穎(Chen TY) 陳城章(Chen CC) 李欣頻(Li HP)

林口長庚紀念醫院
上顎大臼齒之X光根尖片影像,常因其牙根型態與周邊複雜解剖構造投影重疊,造成判讀困難。
本報告分析兩例上顎第一大臼齒進行非手術性根管治療之病例。第一例為初次根管治療(primary root
canal treatment),於測量工作長度(working length)時,根尖片顯示近心頰側(mesiobuccal, MB)根管看
似於髓室底穿孔,經使用顯微鏡(dental operating microscope, DOM)探查確認無穿孔。再以錐狀束電
腦斷層掃描(cone-beam computed tomography, CBCT)影像顯示其近心頰側根寬大,第二近心頰側根管
(MB2 canal)開口遠離近心頰側根管,位於 MB 與腭側(palatal, P)根管開口連線中點。第二例為先前治
療失敗病例,術前根尖片顯示根管充填物於牙根分岔處似有穿孔,顯微鏡下觀察發現腔室底沒有穿孔
情形,CBCT 影像證實該牙具備盛行率小於 1% 的獨立近心腭側根(mesiopalatal root)且被馬來膠(gutta
percha)及樹脂牙柱心(resin core)覆蓋。上顎第一大臼齒之 MB 根出現雙根管之盛行率高達 95%。上述
兩例牙齒之解剖構造因與主根管距離較遠,在二維影像上易呈現類似穿孔假象。若僅依賴根尖片,極
易誤診而導致錯誤的拔牙決策。臨床醫師除應熟悉解剖變異外,亦應結合顯微鏡與 CBCT 進行三維空
間評估,以提升診斷正確性。
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P15

Endodontic Management of Maxillary Second Molar with MB3 Canal: A Case Report

▲ Huang YF Chuang FH*

Department of Dentistry, Kaohsiung Medical University Hospital
The root canal anatomy of the maxillary second molar exhibits high variability. Clinically, the
mesiobuccal (MB) root typically contains one or two canals; however, the occurrence of three independent
canals (MB1, MB2, and MB3) within a single root is extremely rare. This case report demonstrates the
application of cone-beam computed tomography (CBCT) to visualize the complex canal morphology.
Endodontic treatment was facilitated by a dental operating microscope and ultrasonic instruments, and
obturation was completed via warm vertical compaction. In conclusion, maintaining a high index of suspicion
regarding anatomical variations—combined with high-magnification illumination and advanced imaging—
can effectively minimize the risk of missed canals, thereby enhancing treatment quality and long-term success
rates.
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P16

下顎第一大臼齒區之放射線不透性病灶 Radiopaque Lesion in the Posterior Mandible

陳冠宇(Chen KY) ▲1,2 李詔婷 (Lee ST)2 楊瓊宜 (Yang CI)2 宋宜駒 (Sung YC)2 楊正媺 (Yang CM)*2

1高雄榮民總醫院台南分院牙科 2高雄榮民總醫院牙髓病科
下顎後牙區根尖周圍放射線不透性病灶常需鑑別牙髓疾病相關之硬化性骨炎(condensing osteitis)與
非炎性病變,如牙骨質增生(hypercementosis)、牙骨質-骨質發育不良(cemento-osseous dysplasia)及牙骨
質母細胞瘤(cementoblastoma)。本病例報告以同一位40歲女性下顎左右後牙區兩處放射線不透性病灶
為例,探討如何藉由牙周韌帶界線及病灶與牙根之關係,快速判斷病灶源自牙根周圍發炎反應或牙骨
質 (cementum-origin),進而評估其與牙髓疾病之關聯性。病患2年前因左下後牙區放射線不透性病灶
診斷為牙骨質母細胞瘤而拔除左下第一大臼齒,術前牙髓活性測試為陽性,其放射影像呈現與牙根融
合並伴隨完整放射線透射性(radiolucent)暈環。此次因右下第一大臼齒持續脹痛由診所轉診至本院評
估。臨床檢查發現齲齒及敲診疼痛;放射影像顯示患牙已根管治療,遠心牙根尖周圍存在邊界清楚之
放射線不透性病灶,但牙周韌帶界線仍可辨識。綜合臨床與影像檢查,診斷右下第一大臼齒為已根管
治療之症狀型根尖周圍炎(previously treated & symptomatic apical periodontitis),合併牙骨質增生。經根
管再治療後三個月追蹤,症狀消失,根尖周圍放射線透過性區域變小,而放射線不透性病灶無明顯變
化。由此病例顯示,除牙髓活性外,牙周韌帶界線及病灶與牙根之關係可作為臨床快速鑑別骨性病變
與牙骨質來源病變的重要依據,有助於正確診斷並制定適當治療策略。
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P17

根尖周圍炎與根尖礦化生物膜導致牙髓病源性上顎竇炎: 病例報告 Apical Periodontitis and Apical Mineralized Biofilm Leading to Maxillary Sinusitis Endodontic Origin: A Case Report

吳宗隆(Wu CL) ▲*1 張晁熙(Chang CH)2 李雲琪(Li YC)3 孟令成(Meng LC)4

1國泰醫療財團法人國泰綜合醫院口腔醫學部牙髓病科 2國泰醫療財團法人國泰綜合醫院口腔醫學部口腔顎
面外科 3國泰醫療財團法人國泰綜合醫院口腔醫學部家庭牙醫科 4台北醫學大學附設醫院口腔病理科
牙髓病源性上顎竇炎(maxillary sinusitis of endodontic origin, MSEO)是一種常被誤診的疾病。據研
究,在單側上顎竇炎患者中, 因齒源問題引起的比例高達 五至七成。在確診為齒源性的鼻竇炎中,
有高達七成是由牙根尖病變或根管治療不當等牙髓相關問題所引起。根管外感染與根尖礦化生物膜
(apical mineralized biofilm)可能是導致根管治療失敗與持續性根尖牙周炎的原因。當臨床上進行標準的
根管治療或重新治療後仍失敗時,就應當被考慮。本次報告病例為一47歲男性,因左上後牙區腫痛來
院就醫,自述上顎左側單側鼻竇炎反覆發生已半年多,左上後牙牙橋使用已超過10年。經理學及放射
線學影像檢查(包含CBCT),診斷為左上第二大臼齒先前根管治療,症狀性根尖周圍炎合併MSEO。建
議針對該患齒進行根管重新治療,並不排除手術(蓄意再植術)介入的可能。病人經該患齒根管再治療
後單側鼻竇炎症狀依然反反覆覆,改善不大。與病人溝通同意之後,偕同口腔顎面外科醫師進行該患
齒刻意再植術。由於患齒結構缺損較大,於拔除術中發生牙齒斷裂,故整顆拔除,並將根尖周圍病灶
完全挖除。但在其近心頰側牙根尖發現明顯根尖礦化生物膜。病人術後三個月回診,單側鼻竇炎症狀
已完全改善,轉診至本院假牙贗復科,完成後續治療。
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P18

Maxillary Sinusitis of Endodontic Origin: A Case Report

▲ Chen YJ Ou TZ Wang HH*

Wanfang Hospital Taipei Medical University
Maxillary sinusitis of endodontic origin (MSEO) is a specialized condition where periapical pathology
triggers chronic sinonasal inflammation, accounting for up to 40% of unilateral maxillary sinusitis. We present
a 24-year-old female patient with a 6-month history of chronic sinusitis despite repeated ENT treatments.
The Cone-beam computed tomography (CBCT) demonstrated left-sided extensive mucosal opacification with
ostium obstruction, alongside a periapical radiolucency on the previously treated tooth 26 with maxillary sinus
floor perforation. After nonsurgical root canal retreatment under dental operating microscope and concurrent
ENT surgical intervention, complete periapical healing was achieved with sinus floor re-ossification at
the 1-year follow-up . Clinically, the patient reported no discomfort or symptoms. MSEO is frequently
underdiagnosed because sinonasal symptoms often overshadow dental complaints, leading to prolonged
and ineffective ENT treatments. CBCT is an effective modality for the detection and diagnosis of MSEO.
Endodontic retreatment removed the primary infection source of MSEO and ENT surgical intervention is
sometimes required to help restore physiological sinus drainage. Interdisciplinary collaboration is essential
for the timely diagnosis and successful treatment of MSEO.
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P19

Persistent Apical Abscess with Actinomycosis: A Case Report

Li CR ▲1 Chen YH1 Chen KL1 Kuo CY1 Liao IC1 Chen CA*2

1Department of Endodontics, Chi Mei Medical Center, Tainan, Taiwan
2Department of Endodontics, Chi Mei Hospital, Liouying, Tainan, Taiwan
Persistent apical infections following root canal treatment pose clinical challenges, often demanding
both non-surgical and surgical interventions. Actinomycosis, a rare bacterial infection, can further complicate
management, needs a total solution. We report a 27-year-old female presenting with an abscess on the
maxillary right lateral incisor 3 months post-root canal therapy, experiencing severe pain and swelling.
Examination revealed percussion and palpation tenderness, with a radiographic periapical radiolucency
of approximately 18 mm x 14 mm. The diagnosis remained previously initiated therapy and acute apical
abscess. The treatment plan integrated non-surgical retreatment and subsequent apical surgery.Emergency
treatment comprised incision and drainage and a 7-day amoxicillin course. Non-surgical endodontic treatment
was conducted under rubber dam isolation. Once asymptomatic, the canal was obturated utilizing the
lateral condensation technique. Five months later, persistent symptoms necessitated surgical intervention.
A full-thickness mucoperiosteal flap was raised for concurrent periapical curettage and root-end resection.
Retrograde cavity preparation utilized ultrasonic instruments, followed by a root-end filling. Bone grafting was
placed, and the flap sutured.Histopathological analysis confirmed endodontic sealer in the periapical region,
accompanied by distinct bacterial colonies composed of cocci. Identifying multiple colonies with sulfur
granule–like morphology established the diagnosis of actinomycosis. At the 36-month follow-up, the patient
remained asymptomatic, with the periapical lesion completely healed. This case underscores the complexity
of managing persistent apical abscesses with actinomycosis. A multidisciplinary approach integrating non-
surgical retreatment, surgical intervention, and vigilant follow-up proved essential.
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P20

用蓄意再植術與Super-Bond修復下顎大臼齒垂直牙根斷裂: 五年追蹤病例報告 Intentional Replantation of a Vertically Root Fractured Mandibular Molar Repaired with Super-Bond: A Case Report with 5 Years Follow-up

方瑞仁(Fang JJ) ▲*1,2 王佩霜(Wang PS)1 吳政榮(Wu CJ)1 黃彥豪(Huang YH)1

1高雄長庚紀念醫院牙髓病科 2高雄市立鳳山醫院牙科(委託長庚醫療財團法人經營)
患者為48歲女性,主訴為右下第二大臼齒(tooth 47)一個月前開始出現咬合疼痛。六年前患齒因
齲齒而進行根管治療與假牙製作,最近一個月開始有咬合疼痛。患者沒有系統性疾病或是藥物過敏
史,夜間有磨牙的習慣。臨床檢查發現患齒有中度敲診與咬合疼痛,沒有觸診痛,牙齒動搖度在正
常範圍內,牙周囊袋深度在近心頰側為5 mm,其餘位置正常。X光檢查發現tooth 47近心側出現骨缺
損,臨床診斷tooth 47為已根管治療牙齒與症狀型根尖周圍炎(previously treated and symptomatic apical
periodontitis)並且懷疑近心側垂直牙根斷裂。與患者討論治療計畫並告知再植術與牙根斷裂治療效果
的侷限性,患者了解風險後同意先進行患齒再植術治療。手術中發現牙根近心側有垂直牙根斷裂,範
圍由牙根齒頸部延伸到根尖。使用Super-Bond 黏合劑修復垂直牙根斷裂。術後一週移除Coa-Pak與縫
線,傷口癒合良好。術後一個月,裝置臨時假牙。術後八個月,症狀改善後,裝置金屬牙冠。術後一
到三年每年回診檢查,有些許牙周組織發炎,安排定期牙周病維護。術後五年追蹤,tooth 47可以正
常咀嚼,沒有敲診與觸診疼痛,牙周囊袋與牙齒動搖度在正常範圍內。X光檢查可見近心端牙周韌帶
比較寬。整體治療後的結果為具有功能,維持咀嚼功能的狀況下,沒有明顯感染或是發炎的產生。
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P21

使用蓄意牙齒再植術治療醫源性牙根穿孔吸收:病例報告 Management of Iatrogenic Perforating Root Resorption with Intentional Replantation: A Case Report

陳錦(Chen G) ▲*1,2 葉培錚(Yeh PC)1

1臺中榮民總醫院口腔醫學部牙髓病科 2京典美學牙醫診所
牙齒與牙根構造被吸收的原因有生理性,病理性與醫源性等因素。根據Andreasen對牙根吸收的
分類可區分為內吸收與外吸收兩大類。因此,正確診斷與處理可預防後續嚴重破壞。25歲黃姓患者於
2024年11月因牙齦腫脹及疼痛至本院檢診。臨床檢查上顎右側門齒有暫時性牙冠,輕度頰側牙齦發炎
併有觸痛。放射線檢查發現有牙根尖周圍病灶。2024年12月在局部麻醉協助下接受非手術性根管再治
療,橡皮障防濕布隔離後移除封填材料發現有纖維牙根釘柱堵塞。0.2%氯己丁沖洗根管後置放氫氧化
鈣。錐狀射束電腦斷層掃描確認穿孔位於近心頰側處。考慮家屬希望保留牙齒。2025年3月進行牙齒
再植治療,牙齒移出牙齒窩洞後牙根尖以三氧礦化物逆根尖充填,牙根穿孔以四環黴素處理後用生物
陶瓷材料修補,最後置回窩洞以縫線固定。一星期後拆除縫線傷口癒合良好。一、三、六個月後回診
病灶消失,牙根尖及吸收處骨質癒合良好。蓄意牙齒再植是有計畫將受損牙齒移出進行牙根尖手術或
牙根修復。臺中榮總2020年的研究報告指出蓄意牙齒再植1至3年存活率93.1%、87.7%及85.7%。本病
例報告為根管治療失誤導致牙根穿孔及吸收,以蓄意牙齒再植成功完成治療。
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P22

蓄意再植術中應用 DMEM儲存液結合術後藥物輔助策略之探 討:病例報告 Application of DMEM Storage Combined with Postoperative Pharmacological Adjuncts in Intentional Replantation: A Case Report

黃宏秉(Huang HP) ▲1,2 林思洸(Lin SK)*1 李苑玲(Lee YL)1 周佳璇(Chou CH)2

1國立台灣大學醫學院附設醫院口腔醫學部牙髓病科
2國立台灣大學醫學院附設醫院雲林分院牙科部
蓄意再植術(intentional replantation)是針對傳統根管治療或非手術性根管再治療後仍有持續性
病灶,且不適合接受根尖手術之患齒所採取的治療選項。其預後與牙齒離體期間牙周韌帶細胞
(periodontal ligmanet, PDL)活性的維持與牙根吸收的預防密切相關。近期研究關注儲存液與術後藥物
提高蓄意再植術成功率之潛力。本病例為一位 53歲女性,於本院接受下顎右側第二大臼齒非手術性根
管再治療後仍反覆出現頰側膿包,故選擇蓄意再植術。術中患齒拔除後立即置入含有 10% 胎牛血清
(fetal calf serum, FCS)的細胞培養液(Dulbecco’s modified eagle medium, DMEM)中保存。患齒離體期間
完成根尖切除與三氧礦化聚合物(mineral trioxide aggreagate, MTA)逆充填後復位固定,整體離體時間控
制於15 分鐘內。術後搭配短期類固醇、 Statin 類藥物及 Forflow以降低發炎反應並促進血液微循環。
術後追蹤顯示膿包消退、症狀改善,根尖影像可見病灶癒合趨勢。
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P23

具牙根發育溝及副根管之C型根管下顎小臼齒之蓄意再植: 病例報告 Intentional Replantation of a C-Shaped Canal Mandibular Premolar with Radicular Groove and Accessory Canal: A Case Report

余承桓(Yu CH) ▲ 楊臻繹(Yang CY) 韓維美(Harn WM) 詹傑(Chan C)*

彰化基督教醫療財團法人彰化基督教醫院牙髓病科
下顎第一小臼齒C型根管案例較為罕見,根管系統複雜、徹底清創較為困難。C型根管在下顎第
一小臼齒中大約有2.3%的盛行率;甚至在一篇以臺灣人為對象的研究中,下顎第一小臼齒C型根管盛
行率達18%。另外,下顎小臼齒C型根管案例中,具有牙根發育溝(radicular groove)者有很高的比例具
有副根管(accessory canal)。本病例為具C形根管之右下顎第一小臼齒,因疼痛與竇管(sinus tract)由診
所轉診至本院;經非手術性根管治療後竇管持續未消,因此懷疑為副根管構造導致根管清創不完全,
後續安排翻瓣檢視骨缺損區域與蓄意再植。術中將牙齒拔出,以亞甲基藍(methylene blue)染色後在顯
微鏡下觀察;確認沒有裂痕,並且定位副根管開口位置後使用超音波器械清創並進行製備,後採用生
物陶瓷材料(Biodentine®, Septodont, Saint-Maur-des-Fossés, France)對副根管進行逆充填,最後將牙齒植
回合併引導組織再生術(guided tissue regeneration)修復頰側齒槽骨開裂(dehiscence)骨缺損,並施予齒間
固定。術後5個月回診時已無臨床症狀、根尖周圍病灶癒合。對於因根管型態較複雜的下顎小臼齒導
致清創不完全而症狀持續,若非手術治療無法改善症狀時,以蓄意再植搭配超音波器械清創及以生物
陶瓷材料逆充填可改善症狀並獲得良好預後。
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P24

運用第三大臼齒進行自體齒移植:病例報告 Autotransplantation of the Malposition Third Molar: A Case Report

趙妍晴(Chao YC) ▲*1,2 洪瑋成(Hung WC)2,3 宋承恩(Sung CE)2,3 喻大有(Yu DY)2,4 蘇文崧(Su WS)1,2

1三軍總醫院牙科部牙體復形暨牙髓病科 2國防醫學大學口腔醫學院
3三軍總醫院牙科部牙周病科 4三軍總醫院牙科部家庭牙醫暨口腔診斷科
以埋伏齒或已萌發的牙齒從原本位置,移至被拔牙或藉由手術製備的位置,來取代嚴重缺損的
牙齒或重建缺牙的區域,稱為自體齒移植(autotransplantation)。移植齒(donor tooth)的結構、受植區
(recipient site)的狀況、根管治療的時機與品質良好之冠部復形,是治療成功的重要因素,本病例報告
藉由一臨床案例,回顧自體齒移植的適應症、存活率及操作細節。病例為48歲女性,因右下後牙脹痛
不適至本院求診,臨床檢查發現,右側下顎第一大臼齒(tooth 46)具次發性齲齒,有敲痛、觸痛及牙周
囊袋探測深度異常,X光檢查發現根尖周圍有放射線可透性破壞,經顯微鏡檢查後建議拔除患齒。後
續藉由錐狀射束電腦斷層掃描(cone-beam computed tomography, CBCT)評估,與患者討論使用向頰側
旋轉、無咬合功能之左上第三大臼齒(tooth 28)進行自體齒移植,取代嚴重缺損的右側下顎第一大臼
齒。手術前,使用電腦斷層影像與3D列印技術,模擬印製移植齒,於術中協助修整受植區之齒槽窩,
後續進行移植齒之即時移植。手術後,於兩週內安排移植齒顯微根管治療,並完成牙冠復形。治療後
一年回診追蹤,移植齒無明顯動搖度或不適,X光檢查根尖周圍齒槽骨有再生跡象、牙根周圍無明顯
之吸收。
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P25

Management of an Ankylosed Avulsed Immature Incisor: From Apexification to Decoronation

▲ Lin TC Huang HY Tso KY Chiu WC*

School of Dentistry & Department of Dentistry, National Cheng Kung University and National Cheng Kung
University Hospital
Traumatic avulsion of immature permanent teeth may result in pulp necrosis, root resorption, ankylosis,
and subsequent infraocclusion. Management is particularly challenging in growing patients because
progressive infraocclusion may compromise alveolar development and future prosthetic rehabilitation. An
11-year-old boy presented after avulsion of the immature maxillary left central incisor. Following replantation,
pulp necrosis with symptomatic apical periodontitis and inflammatory root resorption were diagnosed.
Because of the wide-open apex, apexification was performed using a mineral trioxide aggregate apical plug.
Periapical healing was achieved; however, replacement resorption and ankylosis became evident during
follow-up. The patient and his parents were informed that decoronation might be required if progressive
infraocclusion developed, and six-monthly monitoring was arranged. At age 14, during the pubertal growth
spurt, infraocclusion exceeded one-quarter of the clinical crown height and mesial tipping of adjacent teeth
was observed. Decoronation was therefore performed to preserve the alveolar ridge, and the clinical crown
was adapted as a natural tooth pontic. At 2.5 years after decoronation, healthy soft tissue contours, preservation
of alveolar ridge dimensions, and continued replacement of the retained root by bone were observed. This case
highlights the importance of long-term monitoring after replantation of immature teeth and demonstrates the
role of decoronation in preserving alveolar ridge dimensions in growing patients.
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P26

Management of Severe Post-Traumatic External Inflammatory Root Resorption in an Immature Permanent Incisor

▲ Huang PH Chen YL Lee YL*

School of Dentistry & Department of Dentistry, National Taiwan University and National Taiwan University Hospital
Managing immature permanent teeth with severe traumatic dental injury-induced external inflammatory
root resorption (EIRR) is highly challenging. This case report describes a 9-year-old boy who underwent
reposition of an avulsed tooth 11 and repositioning of an intrused tooth 21, stablized with flexible splinting
within 1 hour post-injuy. Both teeth had open apices and showed negative responses to pulp vitality tests at
the 2-week splint removal. The patient defaulted on follow-ups, returning two months later with severe EIRR
of tooth 11 and distinct percussion and palpation pain. Pulp necrosis in both teeth was confirmed via the
test cavity. Root canal therapy was initiated, achieving disinfection through passive ultrasonic irrigation and
calcium hydroxide dressing. For tooth 11, additional intracanal corticosteroid medication was applied to arrest
resorption and alleviate symptoms. Given the severe root resorption, short root length, and thin dentinal walls,
tooth 11 was treated with regenerative endodontic procedure (REP). Tooth 21, presenting a more favorable
root morphology, underwent mineral trioxide aggregate (MTA) apexification. At the 48-month follow-up,
both teeth remained functional, showing periapical healing and arrest of root resorption. This case highlights
the importance of comprehensive post-trauma follow-up, early infection control, and appropriate treatment
selection for immature traumatized teeth.
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P27

活髓治療之病例報告 Vital Pulp Therapy: A Case Report

陳佩欣(Chen PH) ▲ 戴岑芳(Tai TF)* 黎永康(Lai WH)

台南市立醫院牙科
近年來隨著活髓治療觀念、顯微鏡技術及生物陶瓷材料如 Biodentine 的發展,其成功率已接近傳
統非手術性根管治療。對於未成熟恆牙,保留活髓有助於牙根持續發育及根尖閉合。本病例為一名
12歲女性,於民國111年8月由診所轉診至本院。臨床及放射線檢查顯示,左上第二小臼齒(tooth 25)及
左上第一大臼齒(tooth 26)皆有深層齲齒,診斷為不可逆性牙髓炎及症狀性根尖周圍炎,其中tooth 25
牙根尚未閉合,tooth 26牙根已發育完成。考量患者年齡及tooth 25未成熟牙之特性,經討論後決定於
顯微鏡輔助下進行活髓治療。移除發炎牙髓組織,並使用浸泡2.5%次氯酸鈉溶液的無菌棉球,於5分
鐘內加壓止血後,以Biodentine 覆蓋,並以玻璃離子體及複合樹脂修復;tooth 26後續以不鏽鋼牙冠進
行全覆蓋修復。術後追蹤2年,兩顆牙齒皆無臨床症狀及放射線異常。然而術後2年餘,tooth 26逐漸
出現根尖病灶,已建議接受非手術性根管治療;tooth 25則於術後3年追蹤時可見牙根持續發育且根尖
孔完全閉合,無臨床及放射線病兆。本病例顯示,顯微鏡輔助活髓治療可作為不可逆性牙髓炎未成熟
恆牙之治療選項,並促進牙根持續發育與根尖閉合。然而即使短期結果良好,成熟恆牙仍可能於長期
追蹤中出現根尖病變,顯示定期追蹤的重要性。
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P28

斷髓治療應用於發育完全之上顎第一大臼齒:病例報告 Pulpotomy in a Young Permanent Upper First Molar: A Case Report

劉昀庭(Liu YT) ▲*1 藍欣(Lan H)1 陳錦松(Chen CS)1,2

1汐止國泰綜合醫院牙科 2國泰綜合醫院牙科
本病例為一位九歲女孩,因左上第一大臼齒嚴重齲齒,由診所轉診至本院牙髓病科就診。口內及
放射學檢查可見左上第一大臼齒咬合面有嚴重齲齒接近牙髓腔,牙根發育接近完成,牙髓活性測試及
冷測試皆為正常。為了盡量保存患者後牙咬合功能及剩餘齒質強度,建議在顯微鏡的輔助下完整移除
齲齒,視牙髓感染程度及狀況評估牙髓治療計劃,首先考慮活髓治療、保留牙髓組織及生理機能,使
根管壁能夠持續增厚及減低傳統根管治療可能引起的併發症。在局部麻醉使用下、橡皮障隔離後於顯
微鏡下仔細移除齲齒,過程中牙髓暴露但仍有未完全移除的齲齒。將齲齒完全移除後並將牙髓腔內感
染出血的牙髓組織移除,並使用生理食鹽水大量沖洗,可見根管內仍存在健康的牙髓組織,於是使用
3%次氯酸鈉溶液沖洗及配合微濕小棉球加壓止血、生物陶瓷(biodentine)覆蓋後,利用光固化玻璃離子
體(Ionoseal)及複合樹脂進行冠部密封,完成斷髓治療(pulpotomy)。左上第一大臼齒進行斷髓治療後,
持續追蹤沒有臨床症狀,且冷測試(cold test)仍有反應,放射學檢查可見牙根管壁厚度有些微增加且根
尖組織正常。21個月後追蹤,左上第一大臼齒根尖組織正常、雙側小臼齒皆已萌發,咬合功能漸趨完
整。本報告探討斷髓治療於年輕恆牙的應用、使用材料及臨床考量。
↑ 回到本頁頂端
P29

牙髓牙周聯合病灶之預後評估與治療管理: 文獻回顧與病例報告 Prognostic Assessment and Management of Endodontic/Periodontic Lesion: A Literature Review and Case Report

李昀庭(Lee YT) ▲1 洪維彊(Hung WC)1,2 張俊偉(Chang CW)1,3 林芯宇(Lin HY)1 王正潔(Wang CC)*1 楊千瑩(Yang CY)1 王秀慧(Wang SH)1

1臺北醫學大學附設醫院 口腔醫學部牙髓病科 2臺北醫學大學 口腔醫學院 口腔衛生學系
3臺北醫學大學 口腔醫學院 牙醫學系
牙髓牙周聯合病灶(endodontic/periodontic lesion)在臨床上面臨極大的決策挑戰。由於牙髓牙周聯
合病灶病因交織且過往缺乏客觀、可量化的評估指標,臨床上常因預後預測的不確定性,導致醫師難
以向患者精確解釋嚴重程度,這往往造成醫病溝通與決策的困難。為打破此臨床困境,本篇藉由探討
目前文獻所提出之客觀預後指標,期望在治療前精確掌握患齒預後,並作為醫病溝通的科學化指引。
文獻指出,牙髓牙周聯合病灶的 5 年存活率可達 85% 以上,然而其預後不應一概而論,而是應取決
於明確的量化因子,包括:骨吸收是否延伸至根尖三分之一、牙周囊袋深度是否大於5毫米、患者是
否抽菸及有無牙周病史。在診斷與預後評估上,錐狀射束電腦斷層掃描(CBCT)扮演關鍵輔助角色,其
三維影像能更清晰地呈現骨破壞型態並輔助偵測多數牙根缺損(如穿孔或吸收),將診斷準確率從傳統
根尖片的 42.2% 提升至 67.2%。引入客觀預後指標並合理運用錐狀射束電腦斷層掃描,能提供更科學
化的決策工具,進而優化醫病溝通並提升患齒的保留率。本篇透過牙髓牙周聯合病灶臨床病例,展示
如何結合上述指標與錐狀射束電腦斷層掃描進行客觀預後評估。
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晚宴行前須知

MUSEUM NIGHT

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2026年8月15日 18:30–21:00
奇美博物館

8月15日大會晚宴須知

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日期2026年8月15日(六)
入館18:30 起
地點奇美博物館

晚宴入場證

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